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製品番号: HY-186197

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RNMT-IN-1

RNMT-IN-1 is a RNMT inhibitor with a pIC₅₀ of 5.5. RNMT-IN-1 can be used for research on various cancers.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 1381321-59-0
分子式: C₁₇H₁₈N₄OS
分子量:326.42

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

RNMT-IN-1 構造式

CAS 番号: 1381321-59-0

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

RNMT-IN-1 is a RNMT inhibitor with a pIC₅₀ of 5.5. RNMT-IN-1 can be used for research on various cancers^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	Inhibition	33.64 % Compound: DDD01060606	Screen against P. berghei liver stage (PbLuc), transformed with Luciferase, at 2uM Screen against P. berghei liver stage (PbLuc), transformed with Luciferase, at 2uM	[PMID: 32078764]
HepG2	Inhibition	-6.8 % Compound: DDD01060606	Toxicity liver stage against HepG2, at 10uM Toxicity liver stage against HepG2, at 10uM	[PMID: 32078764]
HepG2	Inhibition	67.7 % Compound: DDD01060606	Screen against P. berghei liver stage (PbLuc), transformed with Luciferase, at 10uM Screen against P. berghei liver stage (PbLuc), transformed with Luciferase, at 10uM	[PMID: 32078764]

体外実験

RNMT-IN-1 inhibits purified RNMT with a pIC₅₀ of 5.5^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 1381321-59-0
分子量 326.42
分子式 C₁₇H₁₈N₄OS
SMILES

O=C(CC1=CSC=C1)N2CCCC(C2)C3=NNC4=C3C=CC=N4
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. David Porter, et al. Inhibitors of rna methyltransferase. WO2026013291A1. WIPO (PCT). 2025-07-11.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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