NRX-103095
Based on 1 Customer Validation
NRX-103095 is an enhancer of the interaction between β-catenin, and its cognate E3 ligase, SCFβ-TrCP. NRX-103095 enhances the binding of pSer33/Ser37 β-catenin peptide for β-TrCP with an EC50 of 163 nM.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.68%
- CAS 番号: 2763260-38-2
- 分子式: C22H16Cl2F3N3O3S
- 分子量:530.35
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
EC50: 163 nM (β-catenin:β-TrCP Interaction)[1]
化学情報
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CAS 番号 2763260-38-2
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性状 Solid
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分子量 530.35
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分子式 C22H16Cl2F3N3O3S
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Color Off-white to light yellow
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SMILES
O=C(C1=CC=CC(NC(C2=C(C=C(NC2=O)C(F)(F)F)SC3=C(C=CC=C3Cl)Cl)=O)=C1)N(C)C
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (188.55 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8855 mL | 9.4277 mL | 18.8555 mL | 47.1387 mL |
| 5 mM | 0.3771 mL | 1.8855 mL | 3.7711 mL | 9.4277 mL | |
| 10 mM | 0.1886 mL | 0.9428 mL | 1.8855 mL | 4.7139 mL | |
| 15 mM | 0.1257 mL | 0.6285 mL | 1.2570 mL | 3.1426 mL | |
| 20 mM | 0.0943 mL | 0.4714 mL | 0.9428 mL | 2.3569 mL | |
| 25 mM | 0.0754 mL | 0.3771 mL | 0.7542 mL | 1.8855 mL | |
| 30 mM | 0.0629 mL | 0.3143 mL | 0.6285 mL | 1.5713 mL | |
| 40 mM | 0.0471 mL | 0.2357 mL | 0.4714 mL | 1.1785 mL | |
| 50 mM | 0.0377 mL | 0.1886 mL | 0.3771 mL | 0.9428 mL | |
| 60 mM | 0.0314 mL | 0.1571 mL | 0.3143 mL | 0.7856 mL | |
| 80 mM | 0.0236 mL | 0.1178 mL | 0.2357 mL | 0.5892 mL | |
| 100 mM | 0.0189 mL | 0.0943 mL | 0.1886 mL | 0.4714 mL |
NRX-103095 関連分類
HY-141450 関連分類
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