2763260-38-2
2763260-38-2
Chemical Structure
NRX-103095
- CAS No.: 2763260-38-2
- Formula:C22H16Cl2F3N3O3S
- Molecular Weight:530.35
IUPAC Name: 4-((2,6-dichlorophenyl)thio)-N-(3-(dimethylcarbamoyl)phenyl)-2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxamide
InChIKey: BGEHEUAOZPAMKC-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CC(NC(C2=C(C=C(NC2=O)C(F)(F)F)SC3=C(C=CC=C3Cl)Cl)=O)=C1)N(C)C
Biological Activity: NRX-103095 is an enhancer of the interaction between β-catenin, and its cognate E3 ligase, SCFβ-TrCP. NRX-103095 enhances the binding of pSer33/Ser37 β-catenin peptide for β-TrCP with an EC50 of 163 nM[1].
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NRX-103095 | 99.68% | NRX-103095 is an enhancer of the interaction between β-catenin, and its cognate E3 ligase, SCFβ-TrCP. NRX-103095 enhances the binding of pSer33/Ser37 β-catenin peptide for β-TrCP with an EC50 of 163 nM. | ||||||||||||||||||||
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References
Keywords
