2763260-38-2
2763260-38-2
Chemical Structure
NRX-103095
- CAS No.: 2763260-38-2
- Formula:C22H16Cl2F3N3O3S
- Molecular Weight:530.35
IUPAC Name: 4-((2,6-dichlorophenyl)thio)-N-(3-(dimethylcarbamoyl)phenyl)-2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxamide
InChIKey: BGEHEUAOZPAMKC-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CC(NC(C2=C(C=C(NC2=O)C(F)(F)F)SC3=C(C=CC=C3Cl)Cl)=O)=C1)N(C)C
Biological Activity: NRX-103095 is an enhancer of the interaction between β-catenin, and its cognate E3 ligase, SCFβ-TrCP. NRX-103095 enhances the binding of pSer33/Ser37 β-catenin peptide for β-TrCP with an EC50 of 163 nM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NRX-103095 | 99.68% | NRX-103095 is an enhancer of the interaction between β-catenin, and its cognate E3 ligase, SCFβ-TrCP. NRX-103095 enhances the binding of pSer33/Ser37 β-catenin peptide for β-TrCP with an EC50 of 163 nM. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.88
HY-141449NRX-103094 -
Similarity Score 0.64
HY-111836NRX-252114 -
Similarity Score 0.63
HY-111760NRX-252262 -
Similarity Score 0.59
HY-141448NRX-2663 -
Similarity Score 0.51
HY-144984NRX-1933 -
Similarity Score 0.51
HY-144982NRX-1532 -
Similarity Score 0.49
HY-19352T56-LIMKi -
Similarity Score 0.49
HY-18833ALW-II-49-7 -
Similarity Score 0.49
HY-157615HSD17B13-IN-6 -
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