Oligopeptide-10
Based on 1 Customer Validation
Oligopeptide-10 is a bioactive peptide with antimicrobial activity. Oligopeptide-10 exhibits broad-spectrum bactericidal effects against Gram-positive bacteria including Propionibacterium acnes and Staphylococcus aureus. Oligopeptide-10 targets lipoteichoic acid (LTA) on the surface of bacterial cell membranes, induces bacterial osmotic imbalance by disrupting the integrity of bacterial membranes, and reduces the release of pro-inflammatory cytokines induced by bacteria. Oligopeptide-10 possesses skin-protective activity. Oligopeptide-10 can be applied in research related to acne vulgaris, dandruff, seborrheic dermatitis, and tinea pedis.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.91%
- CAS 番号: 466691-40-7
- 分子式: C78H140N20O15
- 分子量:1598.07
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保管条件:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
生物活性
Oligopeptide-10 exhibits broad-spectrum bactericidal effects against Gram-positive bacteria including Propionibacterium acnes and Staphylococcus aureus[1][3].
Oligopeptide-10 exhibits no cytotoxicity, irritation, sensitization, or mutagenicity in in vitro safety evaluations[1].
Oligopeptide-10 binds to lipoteichoic acid (LTA) on the bacterial surface, exerts antimicrobial activity, neutralizes pro-inflammatory bacterial components and reduces inflammatory responses[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 466691-40-7
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性状 Solid
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分子量 1598.07
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分子式 C78H140N20O15
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Color White to off-white
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配列
Phe-Ala-Lys-Ala-Leu-Lys-Ala-Leu-Leu-Lys-Ala-Leu-Lys-Ala-Leu-NH2
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シーケンスの短縮
FAKALKALLKALKAL-NH2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
DMSO : 100 mg/mL (62.58 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.6258 mL | 3.1288 mL | 6.2575 mL | 15.6439 mL |
| 5 mM | 0.1252 mL | 0.6258 mL | 1.2515 mL | 3.1288 mL | |
| 10 mM | 0.0626 mL | 0.3129 mL | 0.6258 mL | 1.5644 mL | |
| 15 mM | 0.0417 mL | 0.2086 mL | 0.4172 mL | 1.0429 mL | |
| 20 mM | 0.0313 mL | 0.1564 mL | 0.3129 mL | 0.7822 mL | |
| 25 mM | 0.0250 mL | 0.1252 mL | 0.2503 mL | 0.6258 mL | |
| 30 mM | 0.0209 mL | 0.1043 mL | 0.2086 mL | 0.5215 mL | |
| 40 mM | 0.0156 mL | 0.0782 mL | 0.1564 mL | 0.3911 mL | |
| 50 mM | 0.0125 mL | 0.0626 mL | 0.1252 mL | 0.3129 mL | |
| 60 mM | 0.0104 mL | 0.0521 mL | 0.1043 mL | 0.2607 mL |