Onfekafusp alfa
Onfekafusp alfa (L19TNF) is a homotrimer that forms from engineered peptides for the L19 antibody in scFv format fused to human TNF. Onfekafusp alfa can be used for malignant glioma research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1957239-88-1
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
[scFv-heavy-kappa]-trimer
Onfekafusp alfa shows a greater anticancer activity than both mTNFα and TN11mTNFα[2].
Onfekafusp alfa shows a 5 to 6 times higher activity than equimolar amounts of recombinant mTNFα and of the fusion protein TN11mTNFα in cytotoxic assay on L-M mouse fibroblasts[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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[scFv-heavy-kappa]-trimer
ELISA, FACS, Functional assay
化学情報
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CAS 番号 1957239-88-1
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SMILES
[Onfekafusp alfa]
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別名
L19TNF
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)