PKM2 activator 7
PKM2 activator 7 (Compd B4) is a PKM2 activator with the AC50 of 0.144 μM. PKM2 activator 7 suppresses DSS (HY-116282C)-induced colitis by inhibiting T cell growth in mouse colitis model.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C16H19F3O4
- 分子量:332.31
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| T-cell | IC50 |
0.43 μM
Compound: B4
|
Antiproliferative activity against concanavalin A-stimulated C57BL/6 mouse T cells measured after 48 hrs by CCK8 assay
Antiproliferative activity against concanavalin A-stimulated C57BL/6 mouse T cells measured after 48 hrs by CCK8 assay
|
[PMID: 38718622] |
化学情報
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分子量 332.31
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分子式 C16H19F3O4
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SMILES
C=C([C@H]1[C@H](O2)[C@H]3[C@@](O3)(C)CC/C=C(COC(F)(F)F)\CC1)C2=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)