Pyclen sulfate
Pyclen sulfate forms kinetically and thermodynamically stable nine-coordinate Ln (III) complexes, as well as Mn (II)-based MRI contrast agents. Pyclen-Based Mn(II) Complexes can be used for liver-specific MRI.
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- CAS 番号: 129135-03-1
- 分子式: C11H20N4O4S
- 分子量:304.37
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
Pyclen can form stable, highly luminescent lanthanide (III) complexes, which serve as one- and two-photon biological probes. These complexes stain living human breast cancer cells, exhibit no significant toxicity in the living Danio rerio (zebrafish) model, and enable high-quality in vivo two-photon microscopy imaging[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 129135-03-1
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分子量 304.37
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分子式 C11H20N4O4S
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SMILES
O=S(=O)(O)O.N=1C2=CC=CC1CNCCNCCNC2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Hamon N, et al. Pyclen-Based Ln(III) Complexes as Highly Luminescent Bioprobes for In Vitro and In Vivo One- and Two-Photon Bioimaging Applications. J Am Chem Soc. 2020 Jun 3;142(22):10184-10197. [Content Brief]
[2]. Hall RC, et al. Manganese(II) EOB-Pyclen Diacetate for Liver-Specific MRI. ACS Appl Bio Mater. 2022;5(2):451-458. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)