Rhizopodin
Rhizopodin is a new cytostatic compound isolated from the culture fluid of the slime mold Myxococcus stipitatus. Rhizopodin inhibits the growth of various animal cell cultures without killing the cells, with an ID50 value of 12 to 30 ng/ml, depending on the cell line. In particular, fibroblast-like cells show typical morphological changes, with cells becoming larger and forming long branched reticular extensions within hours, and these morphological changes are irreversible. Rhizopodin inhibits bleb formation in K-562 cells, possibly through interaction with protein phosphorylation.
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- CAS 番号: 150346-23-9
- 分子式: C78H124N4O22
- 分子量:1469.83
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
化学情報
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CAS 番号 150346-23-9
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分子量 1469.83
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分子式 C78H124N4O22
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SMILES
CO[C@]1([H])C2=COC(C[C@@H](C(C)([C@@H](OC(C[C@H](C[C@H](/C=C/C=C/C[C@@](OC)([H])C3=COC(C[C@H](O)C(C)(C)[C@H](C[C@H](OC)[C@@H](C)CCC([C@H](C)[C@H](OC)C/C=C/N(C)C=O)=O)OC(C[C@@H](O)C[C@@H](OC)/C=C/C=C/C1)=O)=N3)OC)O)=O)C[C@H](OC)[C@@H](C)CCC([C@H](C)[C@H](OC)C/C=C/N(C)C=O)=O)C)O)=N2
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Structure Classification
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Initial Source
Myxococcus stipitatus
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)