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製品番号: HY-126802

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Saquayamycin B1

Saquayamycin B1 has antimicrobial effect, but it has weaker effect against Gram-negative bacteria. Saquayamycin B1 has inhibitory effect on leukemia P388 cells and Adriamycin-resistant P388 cells.

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CAS 番号: 99260-68-1
分子式: C₃₁H₃₂O₁₂
分子量:596.58

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Saquayamycin B1 構造式

CAS 番号: 99260-68-1

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Saquayamycin B1 has antimicrobial effect, but it has weaker effect against Gram-negative bacteria. Saquayamycin B1 has inhibitory effect on leukemia P388 cells and Adriamycin-resistant P388 cells^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
NCI-H460	GI₅₀	13.2 μM Compound: 6	Growth inhibition of human NCI-H460 cells incubated for 48 hrs by resazurin dye reduction based fluorimetric assay Growth inhibition of human NCI-H460 cells incubated for 48 hrs by resazurin dye reduction based fluorimetric assay	[PMID: 22758660]
PC-3	GI₅₀	1.759 μM Compound: 6	Growth inhibition of human PC3 cells incubated for 48 hrs by resazurin dye reduction based fluorimetric assay Growth inhibition of human PC3 cells incubated for 48 hrs by resazurin dye reduction based fluorimetric assay	[PMID: 22758660]

化学情報

CAS 番号 99260-68-1
分子量 596.58
分子式 C₃₁H₃₂O₁₂
SMILES

O=C1C[C@](C)(O)C[C@]2(O)[C@@]1(O)C(C(C3=CC=C([C@H]4C[C@@]5([H])O[C@](CC([C@H](C)O6)=O)([H])[C@]6([H])O[C@]5([H])[C@@H](C)O4)C(O)=C3C7=O)=O)=C7C=C2
Structure Classification
- Antibiotics
- Other Antibiotics
Initial Source
- Microorganisms
Streptomyces sp. XZHG99T
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (268 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Jianjiang Li, et al. Saquayamycin B1 Suppresses Proliferation, Invasion, and Migration by Inhibiting PI3K/AKT Signaling Pathway in Human Colorectal Cancer Cells. Mar Drugs. 2022 Sep 7;20(9):570. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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分子量分子量

希釈計算機

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濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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