L-a-Phosphatidylserine sodium
Based on 1 Customer Validation
L-α-Phosphatidylserine sodium (Soy PS sodium) is a negatively charged phospholipid that acts as an allosteric activator to activate latent plasminogen activator inhibitor-1 (PAI-1). L-α-Phosphatidylserine does not directly alter the catalytic activity of t-PA, but regulates fibrinolytic activity solely by inducing conformational remodeling of PAI-1. L-α-Phosphatidylserine sodium is an antigen targeting phosphatidylserine (PS) and can induce the production of polyclonal antibodies. L-α-Phosphatidylserine is mainly used in studies related to immunology, fibrinolytic system and coagulation homeostasis.
For research use only. We do not sell to patients.
- Purity: 99.0%
- CAS No.: 383908-63-2
-
Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
L-a-Phosphatidylserine sodium activates latent PAI-1 protein purified from the culture supernatant of human umbilical vein endothelial cells, increasing the potency of PAI-1 in inhibiting t-PA by approximately 50-fold[1].
L-a-Phosphatidylserine sodium (> 0.05 mM) achieves saturated maximum activation of PAI-1, whereas sodium dodecyl sulfate requires a concentration exceeding 0.65 mM to reach an equivalent activation effect[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 383908-63-2
-
Appearance Solid
-
Color White to off-white
-
SMILES
[L-a-Phosphatidylserine (sodium)]
-
Synonyms
Soy PS sodium
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
-
Data Sheet (264 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)