SM6.1-azide
SM6.1-azide is a reactant containing an azide group, which can be used in copper-catalyzed azide-alkyne cycloaddition click reactions. SM6.1-azide facilitates the synthesis of trivalent targeted ligand-siRNA conjugates. SM6.1-azide undergoes click chemistry reactions with alkyne-modified oligonucleotides.
For research use only. We do not sell to patients.
- CAS No.: 2320477-40-3
- Formula: C41H51N7O9
- Molecular Weight:785.89
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
SM6.1-azide (3-18.5 equivalents relative to oligo; 0.5-2.5 h) undergoes copper-catalyzed click conjugation with alkyne-modified oligonucleotide, with optimized conditions producing crude yields up to 85.34% and crude purities up to 79.58% while minimizing 2-branch impurities[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2320477-40-3
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Molecular Weight 785.89
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Formula C41H51N7O9
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SMILES
[N-]=[N+]=NCCOCCOCCOCCOCCOC1=CC=C(C2=CC=C(C=C2)[C@H](CC(O)=O)NC(CNC(CCCNC3=CC(C)=CC=N3)=O)=O)C4=C1C=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SM6.1-azide Related Classifications
HY-185425 Related Classifications
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