3,6-Dihydroxyxanthone
Based on 1 publication(s) in Google Scholar
3,6-Dihydroxyxanthone (compound 3) is a xanthone derivatives. 3,6-Dihydroxyxanthone (compound 3) has anticancer activity. 3,6-Dihydroxyxanthone (compound 3) can be used for cancer research.
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- Purity: 98.0%
- CAS No.: 1214-24-0
- 화학식: C13H8O4
- 분자량:228.20
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보관:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) 3,6-Dihydroxyxanthone
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BGC-823 | IC50 |
12.9 μM
Compound: Table S1, R271C2
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Cytotoxicity against human BGC823 cells after 48 hrs by MTT assay
Cytotoxicity against human BGC823 cells after 48 hrs by MTT assay
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[PMID: 30684866] |
| COLO 320 | IC50 |
37.7 μM
Compound: 45370
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Antiproliferative activity against human COLO320 cells after 48 hrs by CCK8 assay
Antiproliferative activity against human COLO320 cells after 48 hrs by CCK8 assay
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[PMID: 28376372] |
| HepG2 | IC50 |
61.7 μM
Compound: 45370
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Antiproliferative activity against human HepG2 cells after 48 hrs by CCK8 assay
Antiproliferative activity against human HepG2 cells after 48 hrs by CCK8 assay
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[PMID: 28376372] |
| K562 | IC50 |
31.2 μM
Compound: 45370
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Antiproliferative activity against human K562 cells after 48 hrs by CCK8 assay
Antiproliferative activity against human K562 cells after 48 hrs by CCK8 assay
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[PMID: 28376372] |
| MCF7 | IC50 |
91.3 μM
Compound: 45370
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Antiproliferative activity against human MCF7 cells after 48 hrs by CCK8 assay
Antiproliferative activity against human MCF7 cells after 48 hrs by CCK8 assay
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[PMID: 28376372] |
| MDA-MB-231 | IC50 |
31.7 μM
Compound: 45370
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Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by CCK8 assay
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by CCK8 assay
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[PMID: 28376372] |
3,6-Dihydroxyxanthone (compound 3) (3.906-1000 μg/mL; 24 hours) exhibits cytotoxic activity against WiDR and Vero cell lines with IC50 values of 785.58 and 1280.9 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:WiDR and Vero cell lines
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Concentration:3.906, 7.813, 15.625, 31.25, 62.5, 125, 250 and 500 µg/mL (WiDR cell line) 7.813, 15.625, 31.25, 62.5, 125, 250, 500 and 1000 µg/mL (Vero cell line)
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Incubation Time:24 hours
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Result:Inhibited cell activity and with IC50 values of 785.58 and 1,280.9 µM for WiDR and Vero cell lines.
Chemical Information
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CAS No. 1214-24-0
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Appearance Solid
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분자량 228.20
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화학식 C13H8O4
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Color White to yellow
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SMILES
O=C1C2=C(OC3=C1C=CC(O)=C3)C=C(O)C=C2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Publications (1)
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Journal Impact Factor
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Most Recent
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Int J Biol Macromol
17-AAG promotes the degradation of HSP90 client METTL3 to suppress MYC RNA m6A modification and expression in colorectal cancer. [Abstract]2025 Dec 3;337(Pt 1):149421. PMID: 41349747
용액&용해도
DMSO : 50 mg/mL (219.11 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.3821 mL | 21.9106 mL | 43.8212 mL | 109.5530 mL |
| 5 mM | 0.8764 mL | 4.3821 mL | 8.7642 mL | 21.9106 mL | |
| 10 mM | 0.4382 mL | 2.1911 mL | 4.3821 mL | 10.9553 mL | |
| 15 mM | 0.2921 mL | 1.4607 mL | 2.9214 mL | 7.3035 mL | |
| 20 mM | 0.2191 mL | 1.0955 mL | 2.1911 mL | 5.4777 mL | |
| 25 mM | 0.1753 mL | 0.8764 mL | 1.7528 mL | 4.3821 mL | |
| 30 mM | 0.1461 mL | 0.7304 mL | 1.4607 mL | 3.6518 mL | |
| 40 mM | 0.1096 mL | 0.5478 mL | 1.0955 mL | 2.7388 mL | |
| 50 mM | 0.0876 mL | 0.4382 mL | 0.8764 mL | 2.1911 mL | |
| 60 mM | 0.0730 mL | 0.3652 mL | 0.7304 mL | 1.8259 mL | |
| 80 mM | 0.0548 mL | 0.2739 mL | 0.5478 mL | 1.3694 mL | |
| 100 mM | 0.0438 mL | 0.2191 mL | 0.4382 mL | 1.0955 mL |
3,6-Dihydroxyxanthone Related Classifications
HY-W031510 Related Classifications
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