Amycolatopsin A
Amycolatopsin A is a 20-membered macrolide, that can be isolated from a strain of the rare actinomycete Amycolatopsis sp. MST‐108494. Amycolatopsin A shows antimycobacterial activity against Mycobacterium bovis (BCG) and M. tuberculosis (H37Rv) with IC50 values of 0.4 µM and 4.4 µM, respectively.
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- CAS No.: 2209112-96-7
- 화학식: C60H98O23
- 분자량:1187.41
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Amycolatopsin A displays significant cytotoxicity against human colon carcinoma (SW620) and lung carcinoma (NCIH-460) cell lines with IC50 values of 0.08 µM and 1.2 µM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2209112-96-7
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분자량 1187.41
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화학식 C60H98O23
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SMILES
C[C@]1([C@H](O[C@](O)([C@@H]([C@H]1O)OC)[C@@H](C2([H])CC(C(/C=C(/C=C(/C=C(C(C(/C=C(/C=C(\C=C(C(O2)=O)/C)OC)CO)C)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)C)OC)O)O)/C)C)C)O)OC)C)CCCOC)O[C@H]4C[C@@H]([C@@H]([C@H](O4)C)O[C@H]5C[C@@](O)([C@@H]([C@H](O5)C)O)C)O
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Structure Classification
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Initial Source
Amycolatopsis sp.
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)