Copy Link Print Information

ATG-031

4 Cited Publications
고객리뷰

Based on 4 publication(s) in Google Scholar

ATG-031 is a humanized anti-CD24 monoclonal antibody with high affinity and specificity. ATG-031 interacts with Siglec-10 expressed by tumor-associated macrophages. ATG-031 effectively stimulates macrophage-mediated phagocytosis and induces cancer cell destruction by blocking the anti-phagocytic surface proteins. ATG-031 can be used in the study of haematological malignancies as well as solid tumors. Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

  • Purity: ≥99%
  • 분자량:146.305 kDa
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for ATG-031
  • Experimental Validation Results for ATG-031
  • Experimental Validation Results for ATG-031
  • ATG-031 Chemical Structure
    ATG-031 Chemical Structure
사이즈
가격
재고
수량
Amount: USD 0.00
Please select quantity
or
or

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
ATG-031 Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
주변의 대리점 찾기 Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Chemical Information
  • 순도&문서
  • References
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products

Publications Citing Use of MedChemExpress (MCE) ATG-031

More
Keywords
MOQ
Minimum order quantity
100 mg

견적 받기 해외재고보유

Other size
견적 받기
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress 로그인
Register
Sign in to MedChemExpress
회원가입

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • 1/16

    Loaded CD24 Protein, Human (Biotinylated, HEK293, His-Avi, HY-P78913) on AHC2 biosensor, can bind ATG-031 with an affinity constant of 8.121E-09 M as determined in BLI assay.

  • 1/16

    Flow cytometric analysis of 1×106 MCF-7 cells labelling CD24 (red) with ATG-031 (HY-P99176). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa Isotype Control (HY-P99003, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • 1/16

    Immobilized Biotinylated Human CD24, at 5 μg/mL (100 μL/well, HY-P78913) on streptavidin precoated (0.5 μg/well) plate, can bind Anti-CD24 Mab (HY-P99176). The ED50 for this effect is 2.899 ng/mL.

  • ATG-031 Chemical Structure
    1/16
  • ATG-031
  • Loaded CD24 Protein, Human (Biotinylated, HEK293, His-Avi, HY-P78913) on AHC2 biosensor, can bind ATG-031 with an affinity constant of 8.121E-09 M as determined in BLI assay.
  • Flow cytometric analysis of 1×106 MCF-7 cells labelling CD24 (red) with ATG-031 (HY-P99176). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa Isotype Control (HY-P99003, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Immobilized Biotinylated Human CD24, at 5 μg/mL (100 μL/well, HY-P78913) on streptavidin precoated (0.5 μg/well) plate, can bind Anti-CD24 Mab (HY-P99176). The ED50 for this effect is 2.899 ng/mL.