Biotin-PEG6-amine
Based on 1 Customer Validation
Biotin-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 2757573-29-6
- 화학식: C24H46N4O8S
- 분자량:550.71
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2757573-29-6
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Appearance Solid
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분자량 550.71
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화학식 C24H46N4O8S
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SMILES
O=C(NCCOCCOCCOCCOCCOCCOCCN)CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 100 mg/mL (181.58 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8158 mL | 9.0792 mL | 18.1584 mL | 45.3959 mL |
| 5 mM | 0.3632 mL | 1.8158 mL | 3.6317 mL | 9.0792 mL | |
| 10 mM | 0.1816 mL | 0.9079 mL | 1.8158 mL | 4.5396 mL | |
| 15 mM | 0.1211 mL | 0.6053 mL | 1.2106 mL | 3.0264 mL | |
| 20 mM | 0.0908 mL | 0.4540 mL | 0.9079 mL | 2.2698 mL | |
| 25 mM | 0.0726 mL | 0.3632 mL | 0.7263 mL | 1.8158 mL | |
| 30 mM | 0.0605 mL | 0.3026 mL | 0.6053 mL | 1.5132 mL | |
| 40 mM | 0.0454 mL | 0.2270 mL | 0.4540 mL | 1.1349 mL | |
| 50 mM | 0.0363 mL | 0.1816 mL | 0.3632 mL | 0.9079 mL | |
| 60 mM | 0.0303 mL | 0.1513 mL | 0.3026 mL | 0.7566 mL | |
| 80 mM | 0.0227 mL | 0.1135 mL | 0.2270 mL | 0.5674 mL | |
| 100 mM | 0.0182 mL | 0.0908 mL | 0.1816 mL | 0.4540 mL |
Biotin-PEG6-amine Related Classifications
HY-140897 Related Classifications
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