Cinnamic acid sodium
Based on 3 publication(s) in Google Scholar
Cinnamic acid sodium is a orally active naturally occurring aromatic fatty acid of low toxicity. Cinnamic acid sodium shows neuroprotective and anti-inflammatory effects.
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- CAS No.: 538-42-1
- 화학식: C9H7NaO2
- 분자량:170.14
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보관:
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Publications Citing Use of MedChemExpress (MCE) Cinnamic acid sodium
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Biological Activity
Cinnamic acid sodium (0.05, 0.4, 3.2 mM; 6, 12, 24 h) induces apoptosis in HT-144 cells in 3.2 mM at 24 h[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:NGM, HT-144 cells
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Concentration:0.05, 0.4, 3.2 mM
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Incubation Time:6, 12, 24 h
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Result:Induced apoptosis in HT-144 cells in 3.2 mM at 24 h, no effect apoptosis in NGM cells.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:6-8 weeks, C57BL/6 mice (18 mg/kg MPTP-HCl, i.p.; at 2-h intervals for 4 times)[1]
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Dosage:100 mg/kg
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Administration:Gavage; starting from 3 h after the last injection of MPTP
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Result:Protected nigral TH levels, protected striatal innervation and neurotransmitters, restored locomotor deficit, increased the activation of Peroxisome Proliferator-Activated Receptor alpha (PPARα) in primary mouse astrocytes, protected striatal TH via PPARα.
Chemical Information
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CAS No. 538-42-1
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분자량 170.14
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화학식 C9H7NaO2
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SMILES
O=C(O[Na])/C=C/C1=CC=CC=C1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (3)
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Journal Impact Factor
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Most Recent
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J Neurosci
2025 Aug 27;45(35):e0523252025. PMID: 40769725 -
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순도&문서
References
[1]. Prorok T, et al. Cinnamic Acid Protects the Nigrostriatum in a Mouse Model of Parkinson's Disease via Peroxisome Proliferator-Activated Receptorα. Neurochem Res. 2019 Apr;44(4):751-762. [Content Brief]
[3]. Niero EL, et al. Cinnamic acid induces apoptotic cell death and cytoskeleton disruption in human melanoma cells. J Exp Clin Cancer Res. 2013 May 23;32(1):31. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cinnamic acid sodium Related Classifications
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