DBCO-PEG6-amine TFA
DBCO-PEG6-amine TFA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. DBCO-PEG6-amine (TFA) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- 화학식: C35H46F3N3O10
- 분자량:725.75
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보관:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All PROTAC Linkers Isoforms
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Biological Activity
Chemical Information
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Appearance Solid
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분자량 725.75
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화학식 C35H46F3N3O10
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Color White to off-white
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SMILES
O=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCC(NCCOCCOCCOCCOCCOCCOCCN)=O.O=C(O)C(F)(F)F
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
용액&용해도
DMSO : 100 mg/mL (137.79 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (264 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3779 mL | 6.8894 mL | 13.7788 mL | 34.4471 mL |
| 5 mM | 0.2756 mL | 1.3779 mL | 2.7558 mL | 6.8894 mL | |
| 10 mM | 0.1378 mL | 0.6889 mL | 1.3779 mL | 3.4447 mL | |
| 15 mM | 0.0919 mL | 0.4593 mL | 0.9186 mL | 2.2965 mL | |
| 20 mM | 0.0689 mL | 0.3445 mL | 0.6889 mL | 1.7224 mL | |
| 25 mM | 0.0551 mL | 0.2756 mL | 0.5512 mL | 1.3779 mL | |
| 30 mM | 0.0459 mL | 0.2296 mL | 0.4593 mL | 1.1482 mL | |
| 40 mM | 0.0344 mL | 0.1722 mL | 0.3445 mL | 0.8612 mL | |
| 50 mM | 0.0276 mL | 0.1378 mL | 0.2756 mL | 0.6889 mL | |
| 60 mM | 0.0230 mL | 0.1148 mL | 0.2296 mL | 0.5741 mL | |
| 80 mM | 0.0172 mL | 0.0861 mL | 0.1722 mL | 0.4306 mL | |
| 100 mM | 0.0138 mL | 0.0689 mL | 0.1378 mL | 0.3445 mL |