Dehydrodeguelin
Dehydrodeguelin (6a,12a-Dehydrodeguelin) is a nature product that could be isolated from the leaves of Amorpha fruticosa L.
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- CAS No.: 3466-23-7
- 화학식: C23H20O6
- 분자량:392.40
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Astrocyte | IC50 |
>80 μM
Compound: 2
|
Growth inhibition of Nf1 defective and Trp53 defective mouse primary astrocytes after 2 hrs by XTT assay
Growth inhibition of Nf1 defective and Trp53 defective mouse primary astrocytes after 2 hrs by XTT assay
|
[PMID: 26467198] |
| B16 | IC50 |
0.56 μM
Compound: 8
|
Cytotoxicity against mouse B16 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against mouse B16 cells assessed as reduction in cell viability by MTT assay
|
[PMID: 28665590] |
| HepG2 | IC50 |
0.56 μM
Compound: 8
|
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay
|
[PMID: 28665590] |
| L5178Y | IC50 |
10.2 μM
Compound: 28
|
Cytotoxicity against mouse L5178Y cells by MTT assay
Cytotoxicity against mouse L5178Y cells by MTT assay
|
[PMID: 28075580] |
| Lewis lung carcinoma cell line | IC50 |
0.56 μM
Compound: 8
|
Cytotoxicity against mouse LL/2 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against mouse LL/2 cells assessed as reduction in cell viability by MTT assay
|
[PMID: 28665590] |
| NCI-H1299 | IC50 |
>500 μM
Compound: 12
|
Cytotoxicity against human H1299 cells after 3 days by MTS assay
Cytotoxicity against human H1299 cells after 3 days by MTS assay
|
[PMID: 23186287] |
Chemical Information
-
CAS No. 3466-23-7
-
분자량 392.40
-
화학식 C23H20O6
-
SMILES
O=C1C2=C(COC3=CC(OC)=C(OC)C=C32)OC4=C5C=CC(C)(C)OC5=CC=C14
-
Synonyms
6a,12a-Dehydrodeguelin
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)