FEN1-IN-2
Based on 1 publication(s) in Google Scholar
FEN1-IN-2 (compound 20) is a flap endonuclease 1 (FEN1) inhibitor, with IC50 values of 3 nM and 226 nM for FEN1 and XPG, respectively.
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- Purity: 99.94%
- CAS No.: 824983-94-0
- 화학식: C20H15N3O4S
- 분자량:393.42
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) FEN1-IN-2
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Biological Activity
IC50: 3 nM (FEN1), 226 nM (XPG)[1].
Chemical Information
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CAS No. 824983-94-0
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Appearance Solid
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분자량 393.42
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화학식 C20H15N3O4S
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Color White to off-white
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SMILES
O=C(C1=CC=C(C2=CC(CN3C(N(C(C4=C3C=CS4)=O)O)=O)=CC=C2)C=C1)N
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
용액&용해도
DMSO : 90 mg/mL (228.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5418 mL | 12.7091 mL | 25.4181 mL | 63.5453 mL |
| 5 mM | 0.5084 mL | 2.5418 mL | 5.0836 mL | 12.7091 mL | |
| 10 mM | 0.2542 mL | 1.2709 mL | 2.5418 mL | 6.3545 mL | |
| 15 mM | 0.1695 mL | 0.8473 mL | 1.6945 mL | 4.2364 mL | |
| 20 mM | 0.1271 mL | 0.6355 mL | 1.2709 mL | 3.1773 mL | |
| 25 mM | 0.1017 mL | 0.5084 mL | 1.0167 mL | 2.5418 mL | |
| 30 mM | 0.0847 mL | 0.4236 mL | 0.8473 mL | 2.1182 mL | |
| 40 mM | 0.0635 mL | 0.3177 mL | 0.6355 mL | 1.5886 mL | |
| 50 mM | 0.0508 mL | 0.2542 mL | 0.5084 mL | 1.2709 mL | |
| 60 mM | 0.0424 mL | 0.2118 mL | 0.4236 mL | 1.0591 mL | |
| 80 mM | 0.0318 mL | 0.1589 mL | 0.3177 mL | 0.7943 mL | |
| 100 mM | 0.0254 mL | 0.1271 mL | 0.2542 mL | 0.6355 mL |
FEN1-IN-2 Related Classifications
HY-122695 Related Classifications
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