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Cat. No.: HY-156415

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NLRP3 agonist 2

NLRP3 agonist 2 (compound 22) is a orally active NLRP3 agonist.NLRP3 agonist 2 activates Caspase-1 in THP1 cells.

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CAS No.: 3049344-69-3
화학식: C₁₄H₁₅N₇
분자량:281.32

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

NLRP3 agonist 2 Chemical Structure

CAS No.: 3049344-69-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

NLRP3 agonist 2 (compound 22) is a orally active NLRP3 agonist.NLRP3 agonist 2 activates Caspase-1 in THP1 cells^[1].

All NOD-like Receptor (NLR) Isoforms :

Chemical Information

CAS No. 3049344-69-3
분자량 281.32
화학식 C₁₄H₁₅N₇
SMILES

NC1=NC(NC2(C)CC2)=C3C(N=C(C=C3)C4=NNC=C4)=N1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. O' Donovan DH, et, al. Discovery and characterisation of quinazolines and 8-Azaquinazolines as NLRP3 agonists with oral bioavailability in mice. Bioorg Med Chem Lett. 2023 Oct 12:96:129518. [Content Brief]

Calculators

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Molecular Weight Molecular Weight

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Chemical Information
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NLRP3 agonist 2

All NOD-like Receptor (NLR) Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

NLRP3 agonist 2 Related Classifications

HY-156415 Related Classifications