NOTA-bis(tBu)ester
Based on 1 Customer Validation
NOTA-bis (tBu) ester is a derivative of NOTA (HY-134418). NOTA-bis (tBu) ester is radiolabeled with 68Ga to form ZD2-(68Ga-NOTA) after conjugation with ZD2. ZD2-(68Ga-NOTA) can be used for PET imaging studies of pancreatic cancer.
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- Purity: 98.0%
- CAS No.: 1161415-28-6
- 화학식: C20H37N3O6
- 분자량:415.52
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
All Radionuclide-Drug Conjugates (RDCs) Isoforms
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Biological Activity
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RDC Bifunctional Chelator |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1161415-28-6
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Appearance Solid
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분자량 415.52
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화학식 C20H37N3O6
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Color White to light yellow
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SMILES
O=C(CN1CCN(CCN(CC1)CC(OC(C)(C)C)=O)CC(OC(C)(C)C)=O)O
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Synonyms
NOTA-bis(t-Butyl ester)
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 50 mg/mL (120.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4066 mL | 12.0331 mL | 24.0662 mL | 60.1656 mL |
| 5 mM | 0.4813 mL | 2.4066 mL | 4.8132 mL | 12.0331 mL | |
| 10 mM | 0.2407 mL | 1.2033 mL | 2.4066 mL | 6.0166 mL | |
| 15 mM | 0.1604 mL | 0.8022 mL | 1.6044 mL | 4.0110 mL | |
| 20 mM | 0.1203 mL | 0.6017 mL | 1.2033 mL | 3.0083 mL | |
| 25 mM | 0.0963 mL | 0.4813 mL | 0.9626 mL | 2.4066 mL | |
| 30 mM | 0.0802 mL | 0.4011 mL | 0.8022 mL | 2.0055 mL | |
| 40 mM | 0.0602 mL | 0.3008 mL | 0.6017 mL | 1.5041 mL | |
| 50 mM | 0.0481 mL | 0.2407 mL | 0.4813 mL | 1.2033 mL | |
| 60 mM | 0.0401 mL | 0.2006 mL | 0.4011 mL | 1.0028 mL | |
| 80 mM | 0.0301 mL | 0.1504 mL | 0.3008 mL | 0.7521 mL | |
| 100 mM | 0.0241 mL | 0.1203 mL | 0.2407 mL | 0.6017 mL |
NOTA-bis(tBu)ester Related Classifications
HY-W250574 Related Classifications
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- NOTA-bis(tBu)ester
- 1161415-28-6
- NOTA-bis(t-Butyl ester)
- Biochemical Assay Reagents
- Radionuclide-Drug Conjugates (RDCs)
- Drug Derivative
- BxPC3 pancreatic tumor
- solid-phase chemistry
- 1,4,7-triazacyclononane-1,4,7-triacetic acid
- Capan-1 pancreatic tumor
- PET
- resin-bound ZD2-HA
- pancreatic cancer
- athymic nu/nu mice
- Ga(III)
- fibroblast activation protein
- Inhibitor
- inhibitor
- inhibit