Reversal of mydriasis by dapiprazole

  • Ann Ophthalmol. 1990 Apr;22(4):131-3, 138.
R W Allinson  1 ,  D S Gerber ,  S Bieber ,  B L Hodes
Affiliations
  • 1. Department of Ophthalmology, University of Arizona, Tucson.
PMID: 1972008
Abstract

The effect of topical dapiprazole, an alpha-adrenergic receptor blocker, in reversing mydriasis was studied in 50 subjects who received tropicamide 1% and phenylephrine 2.5%. There was a significant difference in the decrease in pupil size between the eye that received dapiprazole and the control eye. This study suggests that dapiprazole 0.5% eye drops are effective and safe in reversing mydriasis after instillation of tropicamide 1% and phenylephrine 2.5%.

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