SDH-IN-1
Based on 1 publication(s) in Google Scholar
SDH-IN-1 (compound 4i) is a succinate dehydrogenase (SDH) inhibitor with an IC50 of 4.53 μM. SDH-IN-1 has potent antifungal activities. SDH-IN-1 displays potent activity against S. sclerotiorum (EC50 of 0.14 mg/L).
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 99.95%
- CAS No.: 2685795-52-0
- 화학식: C14H9Cl2N3O2S
- 분자량:354.21
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보관:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) SDH-IN-1
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Biological Activity
Chemical Information
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CAS No. 2685795-52-0
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Appearance Solid
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분자량 354.21
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화학식 C14H9Cl2N3O2S
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Color White to off-white
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SMILES
O=C(C1=NN=C(C2=CC=CS2)O1)NCC3=CC=C(Cl)C(Cl)=C3
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (1)
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Journal Impact Factor
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Most Recent
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EMBO J
SUCLG1 restricts POLRMT succinylation to enhance mitochondrial biogenesis and leukemia progression. [Abstract]2024 Jun;43(12):2337-2367. PMID: 38649537
용액&용해도
DMSO : 16.67 mg/mL (47.06 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (280 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8232 mL | 14.1159 mL | 28.2318 mL | 70.5796 mL |
| 5 mM | 0.5646 mL | 2.8232 mL | 5.6464 mL | 14.1159 mL | |
| 10 mM | 0.2823 mL | 1.4116 mL | 2.8232 mL | 7.0580 mL | |
| 15 mM | 0.1882 mL | 0.9411 mL | 1.8821 mL | 4.7053 mL | |
| 20 mM | 0.1412 mL | 0.7058 mL | 1.4116 mL | 3.5290 mL | |
| 25 mM | 0.1129 mL | 0.5646 mL | 1.1293 mL | 2.8232 mL | |
| 30 mM | 0.0941 mL | 0.4705 mL | 0.9411 mL | 2.3527 mL | |
| 40 mM | 0.0706 mL | 0.3529 mL | 0.7058 mL | 1.7645 mL |
SDH-IN-1 Related Classifications
HY-139983 Related Classifications
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