SN-38 glucuronide-d5
SN-38 glucuronide-d5 (SN-38G-d5) is the deuterium labeled SN-38 glucuronide (HY-126373). SN-38 glucuronide is an inactive metabolite of the anticancer active molecule Irinotecan (HY-16562) and has toxic effects on the gastrointestinal tract. Irinotecan is a topoisomerase I inhibitor which can be used for researching colon and rectal cancer.
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- 화학식: C28H23D5N2O11
- 분자량:573.56
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 121080-63-5
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분자량 573.56
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화학식 C28H23D5N2O11
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SMILES
O=C1OCC2=C([C@]1(CC)O)C=C3C4=NC5=CC=C(C=C5C(C([2H])([2H])C([2H])([2H])[2H])=C4CN3C2=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C(O)=O)O)O)O
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Synonyms
SN-38G-d5
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)