VCAM1 binding peptide
VCAM1 binding peptide is a VCAM1 binder with internalization activity. VCAM1 binding peptide can be labeled with 5-FAM. VCAM1 binding peptide serves as a component of biosensing systems for visualizing in vitro VCAM1 endocytic pathways. VCAM1 binding peptide forms the research and development basis for MacroP and NAMP, PET radiotracers targeting VCAM1. VCAM1 binding peptide is applicable to studies related to atherosclerosis.
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- CAS No.: 1311293-04-5
- 화학식: C57H95N23O16S
- 분자량:1390.57
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
All Radionuclide-Drug Conjugates (RDCs) Isoforms
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Biological Activity
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RDC Peptide |
The binding intensity of 5FAM-labeled VCAM1-binding peptide (10 mM; 4 h) to TNFα-treated HUVEC is higher than that to control HUVEC[1].
68Ga-MacroP (a VCAM1-binding peptide conjugate) binds specifically to VCAM-1 on the surface of TNF-α-stimulated HUVECs, and the activated cellular radioactive uptake is 4-fold higher than that of unstimulated control cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1311293-04-5
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분자량 1390.57
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화학식 C57H95N23O16S
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Sequence
Val-His-Pro-Lys-Gln-His-Arg-Gly-Gly-Ser-Lys-Gly-Cys
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Sequence Shortening
VHPKQHRGGSKGC
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
VCAM1 binding peptide Related Classifications
HY-P11088 Related Classifications
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