KTX-582 intermediate-1

Cat. No.: HY-49436 Pureza: 98.61%: Ficha de datos
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KTX-582 intermediate-1 is an intermediate in the synthesis of KTX-582 (HY-148274) and can be used for ADC preparation. KTX-582 is an IRAK4 degrader and inducer of apoptosis with DC_{50_{of 4 nM and 5 nM for IRAK4 and Ikaros, respectively^{[1]^.}}}

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KTX-582 intermediate-1 Estructura química

No. CAS : 845508-29-4

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5 mg	En stock	Estimated Time of Arrival: December 31
10 mg	En stock	Estimated Time of Arrival: December 31
25 mg	En stock	Estimated Time of Arrival: December 31
50 mg	En stock	Estimated Time of Arrival: December 31
100 mg	En stock	Estimated Time of Arrival: December 31
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Descripciòn

Peso molecular

326.41

Fòrmula

C₁₆H₂₂O₅S

No. CAS

845508-29-4

Appearance

Solid

Color

Off-white to light yellow

SMILES

CCOC([C@@H](CC1)CC[C@@H]1OS(=O)(C2=CC=C(C=C2)C)=O)=O

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Pureza y Documentación

Purity: 98.61%

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Ficha de datos (265 KB) SDS (393 KB)

COA (246 KB) HNMR (147 KB) LCMS (94 KB)

Instrucciones de manejo (2659 KB)

Referencias

[1]. Mainolfi, et al. Preparation of heterocycles as IRAK degraders and uses thereof. World Intellectual Property Organization, WO2022147465 A1. 2022-07-07.