3 Results for "

leptomycin-b

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "leptomycin-b" in MCE Product Catalog:

25
25 Cited Publications
Cat. No.: HY-16909
CAS No.: 87081-35-4
Synonyms: CI 940; LMB
Target:  

CRM1 Fungal Antibiotic

Research Areas:  

Infection Cancer

Leptomycin B (CI 940; LMB) is a potent inhibitor of the nuclear export of proteins. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue. Leptomycin B is a potent antifungal antibiotic blocking the eukaryotic cell cycle .
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Cat. No.: HY-164710
Synonyms: b-LMB
Target:  

CRM1

Research Areas:  

Others

Biotinylated leptomycin B is a compound used to quantify nuclear export protein 1 (XPO1) occupancy and is used to study the interaction of SINE compounds with XPO1 and the response of cancer cells to related compounds.
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Cat. No.: HY-N6795
CAS No.: 87081-36-5
Leptomycin A, a Streptomyces metabolite, is an inhibitor of CRM1 (exportin 1) that blocks CRM1 interaction with nuclear export signals, preventing the nuclear export of a broad range of proteins. Leptomycin A suppresses HIV-1 replication. Less potent than Leptomycin B .
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