2. Anti-infection
  3. Fungal
  4. Macrocarpal C

Macrocarpal C can be isolated from the 95 % ethanol extract of fresh leaves of E. globulus. Macrocarpal C inhibits the growth of T. mentagrophytes via an increase in the permeability of the fungal membrane. Macrocarpal C increases the production of intracellular ROS and? induces apoptosis as a consequence of DNA fragmentation.

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Macrocarpal C

Macrocarpal C Estructura química

No. CAS : 142628-53-3

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Macrocarpal C Related Antibodies

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Descripciòn

Macrocarpal C can be isolated from the 95 % ethanol extract of fresh leaves of E. globulus. Macrocarpal C inhibits the growth of T. mentagrophytes via an increase in the permeability of the fungal membrane. Macrocarpal C increases the production of intracellular ROS and? induces apoptosis as a consequence of DNA fragmentation[1].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
< 10 μM
Compound: Macrocarpal C
Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
[PMID: 27142786]
HL-60 IC50
< 10 μM
Compound: Macrocarpal C
Cytotoxicity against human HL60 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human HL60 cells assessed as reduction in cell viability after 72 hrs by MTT assay
[PMID: 27142786]
Peso molecular

454.60

Fòrmula

C28H38O5
No. CAS
Appearance

Solid

Color

White to light yellow

SMILES

CC(C)C[C@@H](C1=C(C(C=O)=C(C(C=O)=C1O)O)O)[C@@]2([C@@]3([H])[C@@]4([H])[C@](CCC([C@]3([H])CC2)=C)([H])C4(C)C)C
Structure Classification
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

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Referencias
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Macrocarpal C Related Classifications

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Keywords:

Macrocarpal C142628-53-3FungalNatural ProductsROSApoptosisInhibitorinhibitorinhibit

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Nombre del producto:
Macrocarpal C
Cat. No.:
HY-N3344
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