S-312

S-312 is a calcium antagonist with a bicyclic dihydrothienopyridine structure. S-312 can relax the helical strips of various isolated rabbit arteries procontracted with high potassium depolarizaiton. S-312 competitively imhibits calcium-induced contractions in depolarized basilar and femoral arteries. S-312 increases AV nodal conduction time in Langenedorff-perfused isolated rabbit hearts. S-312 exhibits vasculoselectivity, particularly for cerebral vessel.

For research use only. We do not sell to patients.

  • CAS No.: 120004-07-1
  • Formula: C20H22N2O4S
  • Molecular Weight:386.46
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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