47 Results for "

cell-lysis

" in MedChemExpress (MCE) Product Catalog:
Products (47)

47 Results for "cell-lysis" in MCE Product Catalog:

10
Cardiotoxin Analog (CTX) IV (6-12)
Cardiotoxin Analog (CTX) IV (6-12)
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10 Publications Verification
製品番号: HY-P1902
CAS 番号: 115722-23-1
Category:  

Cardiovascular Disease 天然物 Animals Disease Research Fields

Target:  

Apoptosis

Cardiotoxin Analog (CTX) IV (6-12) is a membrane active peptide that specifically targets negatively charged phospholipid membranes (such as phosphatidylserine and phosphatidylinositol). Cardiotoxin Analog (CTX) IV (6-12) was discovered in the venom of the Taiwan cobra. Cardiotoxin Analog (CTX) IV (6-12) is a chemically synthesized snake venom cardiotoxin that binds to cell membranes and embeds into lipid bilayers through hydrophobic interactions and electrostatic attraction, thereby destroying the stability of membrane structure. Cardiotoxin Analog (CTX) IV (6-12) can induce membrane lipid disorder and cell lysis, exhibiting hemolysis and cytotoxicity .
10
Cardiotoxin Analog (CTX) IV (6-12) TFA
Cardiotoxin Analog (CTX) IV (6-12) TFA
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10 Publications Verification
製品番号: HY-P1902A
CAS 番号: 2918768-05-3
Category:  

Pyrrole Alkaloids Animals Other Diseases Disease Research Fields

Target:  

Apoptosis

Cardiotoxin Analog (CTX) IV (6-12) TFA is a membrane active peptide that specifically targets negatively charged phospholipid membranes (such as phosphatidylserine and phosphatidylinositol). Cardiotoxin Analog (CTX) IV (6-12) TFA was discovered in the venom of the Taiwan cobra. Cardiotoxin Analog (CTX) IV (6-12) TFA is a chemically synthesized snake venom cardiotoxin that binds to cell membranes and embeds into lipid bilayers through hydrophobic interactions and electrostatic attraction, thereby destroying the stability of membrane structure. Cardiotoxin Analog (CTX) IV (6-12) TFA can induce membrane lipid disorder and cell lysis, exhibiting hemolysis and cytotoxicity .
4
Ceftiofur sodium
Ceftiofur sodium
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4 Cited Publications
製品番号: HY-B0898
CAS 番号: 104010-37-9
別名: sodium ceftiofur
Target:  

Antibiotic Bacterial NF-κB p38 MAPK TNF Receptor Interleukin Related

研究分野:  

Infection

Ceftiofur sodium is a cell wall synthesis inhibitor that targets bacterial penicillin-binding proteins (PBPs) and has anti-inflammatory effects in endotoxemia. Ceftiofur sodium exerts bactericidal effects by inhibiting the synthesis of bacterial cell wall peptidoglycan, leading to bacterial cell lysis. Ceftiofur sodium also inhibits the activation of NF-κB and MAPKs, thereby reducing the secretion of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6 .
4
Ceftiofur
Ceftiofur
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4 Cited Publications
製品番号: HY-N7102
CAS 番号: 80370-57-6
Target:  

Antibiotic Bacterial NF-κB p38 MAPK TNF Receptor Interleukin Related

研究分野:  

Infection

Ceftiofur is a cell wall synthesis inhibitor that targets bacterial penicillin-binding proteins (PBPs) and has anti-inflammatory effects in endotoxemia. Ceftiofur exerts bactericidal effects by inhibiting the synthesis of bacterial cell wall peptidoglycan, leading to bacterial cell lysis. Ceftiofur also inhibits the activation of NF-κB and MAPKs, thereby reducing the secretion of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6 .
4
Ceftiofur hydrochloride
Ceftiofur hydrochloride
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4 Cited Publications
製品番号: HY-B0026
CAS 番号: 103980-44-5
Target:  

Antibiotic Bacterial NF-κB p38 MAPK TNF Receptor Interleukin Related

研究分野:  

Infection

Ceftiofur hydrochloride is a cell wall synthesis inhibitor that targets bacterial penicillin-binding proteins (PBPs) and has anti-inflammatory effects in endotoxemia. Ceftiofur hydrochloride exerts bactericidal effects by inhibiting the synthesis of bacterial cell wall peptidoglycan, leading to bacterial cell lysis. Ceftiofur hydrochloride also inhibits the activation of NF-κB and MAPKs, thereby reducing the secretion of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6 .
3
n-Octyl β-D-glucopyranoside
n-Octyl β-D-glucopyranoside
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3 Cited Publications
製品番号: HY-116285
CAS 番号: 29836-26-8
純度:  99.92%
n-Octyl-β-d-glucopyranoside is a non-ionic detergent, it can be widely used in the research of biotechnical, biochemical applications, solubilization and crystallization of membrane proteins. n-Octyl-β-d-glucopyranoside can completely inhibit cavitation-induced cell lysis in vitro .
3
Desthiobiotin-Iodoacetamide
Desthiobiotin-Iodoacetamide
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3 Cited Publications
製品番号: HY-150230
CAS 番号: 2924824-04-2
純度:  99.51%
Target:  

ADC Linkers

研究分野:  

Cancer

Desthiobiotin-Iodoacetamide can be used as an ADC Linker. Desthiobiotin-Iodoacetamide also acts as a probe used to label the the Oridonin (HY-N0004)-treated cell lysis .
1
Perforin-IN-2
Perforin-IN-2
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1 Cited Publications
製品番号: HY-160214
CAS 番号: 1567836-70-7
Target:  

Complement System

研究分野:  

Inflammation/Immunology Cancer

Perforin-IN-2 (Compound 1) is the inhibitor for perforin that inhibits perforin-mediated cell lysis, thereby reducing graft rejection during allogeneic bone marrow/stem cell transplantation .
1
SMAP-29
SMAP-29
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1 Cited Publications
製品番号: HY-P2460
CAS 番号: 172485-26-6
Target:  

Bacterial Fungal Interleukin Related TNF Receptor

研究分野:  

Infection Inflammation/Immunology

SMAP‑29 is a cathelicidin antimicrobial peptide with LPS‑binding and anti‑inflammatory properties. SMAP‑29 exerts broad‑spectrum antimicrobial activity against bacteria, fungi and multidrug‑resistant isolates. SMAP‑29 kills pathogens by permeabilizing bacterial membranes, inducing depolarization and cell lysis, and also inhibits inflammatory cytokines while reducing lethality in septic shock and pneumonia models. SMAP-29 can be used for research on bacterial infections, drug-resistant infections, septic shock .
1
XmAb 5592
XmAb 5592
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1 Cited Publications
製品番号: HY-P99381
CAS 番号: 1221901-33-2

Target:  

Transmembrane Glycoprotein

研究分野:  

Cancer

XmAb 5592 is a humanized, Fc-engineered anti-HM1.24 antibody with enhanced binding to FcγRIIIa and FcγRIIa receptors, augments HM1.24-specific multiple myeloma (MM) cells lysis in vitro via antibody-dependent cellular cytotoxicity (ADCC) and antibody dependent cellular phagocytosis (ADCP) .
1
Red Blood Cell Lysis Buffer (10×)
Red Blood Cell Lysis Buffer (10×)
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1 Cited Publications
製品番号: HY-K3010

MCE Red Blood Cell Lysis Buffer (10×) primarily contains ammonium chloride and is a ready-to-use solution designed for rapid and effective lysis and removal of anucleated red blood cells from human or mouse blood and tissue samples without affecting white blood cells, normal tissues, or tumor cells.

Teclistamab
Teclistamab
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製品番号: HY-P99392
CAS 番号: 2119595-80-9
別名: JNJ-7957; JNJ-64007957; Tecvayli

Target:  

CD3

研究分野:  

Cancer

Teclistamab is a human bispecific antibody to BCMA and CD3 that recognizes BCMA on target cells and CD3 on T cells and induces T cell-mediated cytotoxicity leading to T cell activation and subsequent target cell lysis. Teclistamab can be used in studies of diseases related to multiple myeloma (MM) .
Surovatamig
Surovatamig
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製品番号: HY-P991028
CAS 番号: 2892667-02-4
別名: AZD0486; TNB-486

Target:  

CD3 CD19 Interleukin Related TNF Receptor IFNAR

研究分野:  

Cancer

Surovatamig (AZD0486; TNB-486) is a fully human anti-CD19/CD3 IgG4 bispecific antibody. Surovatamig triggers T cell activation, releases cytotoxic granules, and induces T cell-dependent cellular cytotoxicity and tumor cell lysis. Surovatamig can reduces release of pro-inflammatory cytokines including IL-2, IFNγ, TNF. Surovatamig can be used for the research of cancer, such as B cell non-Hodgkin lymphoma .
Xaluritamig
Xaluritamig
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製品番号: HY-P990688
CAS 番号: 2559056-68-5
別名: AMG-509

Target:  

CD3

研究分野:  

Cancer

Xaluritamig (AMG-509) is a bispecific T cell engager and cytolytic agent with a Kd of 27.6 nM for human CD3ε. Xaluritamig binds to CD3ε via an anti-CD3 single-chain variable fragment (scFv) domain, and to STEAP1 via a bispecific anti-STEAP1 antigen-binding fragment (Fab) domain, thereby recruiting and activating T cells and forming a bridge between T cells and STEAP1-expressing cancer cells. Xaluritamig induces T cell-mediated redirected cytotoxicity, tumor cell lysis, cytokine release, CD8 + T cell activation and expansion, as well as tumor stasis or regression. Xaluritamig contains an Fc domain with no effector function, which prolongs serum half-life, exhibits only minimal activity against cells with low STEAP1 expression and normal cells, and shows extremely low target-related off-tumor toxicity in cynomolgus monkeys. Xaluritamig is used in STEAP1×CD3 XmAb 2+1 immunotherapy and in research on metastatic castration-resistant prostate cancer and Ewing sarcoma .
Etevritamab
Etevritamab
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製品番号: HY-P99948
CAS 番号: 2329692-74-0
別名: AMG-596

Target:  

EGFR CD3

研究分野:  

Neurological Disease Cancer

Etevritamab (AMG-596) is a bispecific T-cell engager that targets EGFRvIII and CD3. Etevritamab simultaneously binds CD3 on T cells and EGFRvIII on glioblastoma multiforme cells, thereby forming a bridge structure. Etevritamab triggers T-cell activation, proliferation, secretion of cytotoxic substances, and tumor cell lysis. Etevritamab extends overall survival and induces tumor regression in mouse models of glioblastoma multiforme. Etevritamab can be used for research related to glioblastoma .
Pexiganan
Pexiganan
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製品番号: HY-105088
CAS 番号: 147664-63-9
純度:  99.31%
別名: MSI 78 free base
Category:  

Infection 天然物 Animals Disease Research Fields

Target:  

Bacterial

Pexiganan (MSI 78) is an orally active antimicrobial peptide with broad-spectrum bactericidal. Pexiganan disrupts bacterial cell membranes, induces peptidoglycan damage and cell lysis. Pexiganan TFA can be used for the research of bacterial infection .
TXA707
TXA707
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製品番号: HY-153695
CAS 番号: 1609670-89-4
Target:  

Bacterial

研究分野:  

Infection

TXA707 is an FtsZ-targeting antibacterial agent. TXA707 disrupts bacterial septum formation, induces cell enlargement, causes penicillin-binding protein mislocalization, and triggers cell lysis in Staphylococcus aureus cells. TXA707 can be used for the research of Staphylococcus aureus infections .
PNC-27
PNC-27
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製品番号: HY-P3508
CAS 番号: 1159861-00-3
Target:  

MDM-2/p53

研究分野:  

Cancer

PNC-27, a chimeric p53-penetratin peptide binds to HDM-2 in a p53 peptide-like structure, induces selective membrane-pore formation and leads to cancer cell lysis. PNC-27 is an anticancer peptide. PNC-27 can be used in acute myeloid leukemia research .
Tetradecyl sulfate sodium
Tetradecyl sulfate sodium
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製品番号: HY-W195048
CAS 番号: 1191-50-0
Target:  

Biochemical Assay Reagents

研究分野:  

Cancer

Tetradecyl sulfate sodium is an anionic detergent sclerosant. Tetradecyl sulfate sodium disturbs phospholipid cell membranes, causing membrane solubilization and cell lysis at high concentrations, and creates endothelial cell membrane negative charge to induce coagulation, thrombotic occlusion, fibrosis, and vessel ablation at lower concentrations. Tetradecyl sulfate (sodium) can be used for the research of hemangioma, Kaposi sarcoma, lymphangioma circumscriptum .
Delta-hemolysin
Delta-hemolysin
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製品番号: HY-P5492
CAS 番号: 74838-20-3
別名: Delta-lysin
Target:  

Bacterial

研究分野:  

Others

Delta-hemolysin (Delta-lysin), a 26 amino acid peptide, is a hemolytic peptide produced by Staphylococcus. Delta-hemolysin may slightly perturb a membrane or lead to cell lysis. Delta-hemolysin is a model in the study of peptides interacting with membranes. Delta-hemolysin is poorly active against bacteria .
Assay Types