2. Recombinant Proteins
  3. Cytokines and Growth Factors
  4. CSF & Receptors
  5. GM-CSFR
  6. GM-CSF R alpha

GM-CSF R alpha

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GM-CSF R alpha is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2. GM-CSF R alpha binds to the cytokine with high specificity and low affinity[1]. GM-CSF R alpha binds to GM-CSF and induces cell differentiation[2]. GM-CSF R alpha monoclonal antibody decreases GM-CSFRα expression on GM-CSF-responsive cells and shows anti-inflammatory activity in rheumatoid arthritis (RA)[3].

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Cat. No. Product Name / Synonyms Species Source
  • HY-P73083
    GM-CSF R alpha Protein, Human (HEK293, Fc)

    Granulocyte-macrophage colony-stimulating factor receptor subunit alpha; GMR-alpha; CD116; CSF2RA; CSF2R; CSF2RY

    		Human HEK293
    GM-CSF R alpha is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2. GM-CSF R alpha binds to the cytokine with high specificity and low affinity. GM-CSF R alpha binds to GM-CSF and induces cell differentiation. GM-CSF R alpha monoclonal antibody decreases GM-CSFRα expression on GM-CSF-responsive cells and shows anti-inflammatory activity in rheumatoid arthritis (RA). GM-CSF R alpha Protein, Human (HEK293, Fc) is a recombinant protein with a C-Terminal Fc label, It consists of 320 amino acids (M1-G320) and is produced in HEK293 cells.
  • HY-P7783
    GM-CSF R alpha Protein, Human (HEK293, His)

    rHuCD116, His; Granulocyte-Macrophage Colony-Stimulating Factor Receptor Subunit Alpha; CD116; CSF2RA; CSF2R; CSF2RY

    		Human HEK293
    GM-CSF R alpha is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2. GM-CSF R alpha binds to the cytokine with high specificity and low affinity. GM-CSF R alpha binds to GM-CSF and induces cell differentiation. GM-CSF R alpha monoclonal antibody decreases GM-CSFRα expression on GM-CSF-responsive cells and shows anti-inflammatory activity in rheumatoid arthritis (RA). GM-CSF R alpha Protein, Human (HEK293, His) is a recombinant protein with a C-Terminal His label, It consists of 298 amino acids (E23-G320) and is produced in HEK293 cells.
  • HY-P78110
    GM-CSF R alpha Protein, Human (Biotinylated, HEK293, His-Avi)

    GM-CSF-R-alpha; GMCSFR-alpha; GMR-alpha; CSF2R; CSF2RY; CSF2RA; CDw116; CD116; CSF2RAX; CSF2RAY; CSF2RX; GMCSFR; GMR; SMDP4

    		Human HEK293
    GM-CSF R alpha is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2. GM-CSF R alpha binds to the cytokine with high specificity and low affinity. GM-CSF R alpha binds to GM-CSF and induces cell differentiation. GM-CSF R alpha monoclonal antibody decreases GM-CSFRα expression on GM-CSF-responsive cells and shows anti-inflammatory activity in rheumatoid arthritis (RA). GM-CSF R alpha Protein, Human (Biotinylated, HEK293, His-Avi) is a biotinylated recombinant protein with a C-Terminal His label and a C-Terminal Avi label, It consists of 298 amino acids (E23-G320) and is produced in HEK293 cells.
  • HY-P700730
    GM-CSF R alpha Protein, Cynomolgus (298.a.a, HEK293, His)

    GM-CSF-R-alpha; GMCSFR-alpha; GMR-alpha; CSF2R; CSF2RY; CSF2RA; CDw116; CD116; CSF2RAX; CSF2RAY; CSF2RX; GMCSFR; GMR; SMDP4

    		Cynomolgus HEK293
    GM-CSF R alpha Protein, a crucial type I cytokine receptor in the Type 5 subfamily, plays an essential role in mediating cellular responses to various cytokines. Sharing conserved features with related receptors, it transduces signals from specific type I cytokines, emphasizing its unique contributions to hematopoiesis and immune regulation within the broader context of cell signaling. Understanding GM-CSF R alpha's role holds promise for therapeutic interventions in hematopoietic disorders and immune dysregulation. GM-CSF R alpha Protein, Cynomolgus (298.a.a, HEK293, His) is the recombinant cynomolgus-derived GM-CSF R alpha protein, expressed by HEK293, with C-His labeled tag. The total length of GM-CSF R alpha Protein, Cynomolgus (298.a.a, HEK293, His) is 298 a.a., with molecular weight of 60-70 kDa.
  • HY-P77909
    GM-CSF R alpha Protein, Mouse (HEK293, His)

    GM-CSF-R-alpha; GMCSFR-alpha; GMR-alpha; CSF2R; CSF2RY; CSF2RA; CDw116; CD116; CSF2RAX; CSF2RAY; CSF2RX; GMCSFR; GMR; SMDP4

    		Mouse HEK293
    GM-CSF R alpha is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2. GM-CSF R alpha binds to the cytokine with high specificity and low affinity. GM-CSF R alpha binds to GM-CSF and induces cell differentiation. GM-CSF R alpha monoclonal antibody decreases GM-CSFRα expression on GM-CSF-responsive cells and shows anti-inflammatory activity in rheumatoid arthritis (RA). GM-CSF R alpha Protein, Mouse (HEK293, His) is a recombinant protein with a C-Terminal His label, It consists of 298 amino acids (L30-P327) and is produced in HEK293 cells.
Cat. No. Product Name Effect Purity