11 Results for "

tweak-r

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "tweak-r" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P72434
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF12A; Fibroblast growth factor-inducible immediate-early response protein 14; FN14; CD266 antigen and tweak-receptor
Species:  
Source:  
Cat. No.: HY-P99361
CAS No.: 1062149-33-0
Synonyms: PDL192; ABT-361; Anti-TNFRSF12A/tweakR/CD266 Reference Antibody (enavatuzumab)

Target:  

TNF Receptor

Research Areas:  

Cancer

Enavatuzumab (PDL192; ABT-361) is a humanized IgG1 monoclonal antibody targeting the receptor of TNF-like weak inducer of apoptosis (TWEAK). TWEAK (Fn14; TNFRSF12A), the natural ligand of the TWEAK receptor (TweakR), stimulates multiple cellular responses. Enavatuzumab induces tumor growth inhibition through direct TweakR signaling and antibody dependent cell-mediated cytotoxicity (ADCC). Enavatuzumab can actively recruits and activates myeloid effectors to kill tumor cells. Enavatuzumab inhibits the growth of various human TweakR-positive cancer cell lines and xenografts in vitro and in vivo .
Cat. No.: HY-P991439

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

BIIB023 is a human monoclonal antibody (mAb) targeting TNFRSF12A/TWEAKR/CD266. BIIB023 can be used in lupus nephritis and rheumatoid arthritis research .
Cat. No.: HY-RS14803
Research Areas:  

Others

TNFRSF12A Human Pre-designed siRNA Set A contains three designed siRNAs for TNFRSF12A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.: HY-RS17480
Research Areas:  

Others

Tnfrsf12a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tnfrsf12a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.: HY-P71909
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD 266; CD266; CD266 antigen; FGF inducible 14; FGF-inducible 14; Fibroblast growth factor inducible immediate early response protein 14; Fibroblast growth factor-inducible immediate-early response protein 14; FN 14; FN14; TNFRSF 12A; TNFRSF12A; TNR12_HUMAN; Tumor necrosis factor receptor superfamily member 12A; tweak R; tweak receptor; tweak-receptor; tweakR
Species:  
Source:  
Cat. No.: HY-P992321

Target:  

TNF Receptor NF-κB STAT

Research Areas:  

Cancer

BAY-356, a potent TWEAK receptor agonist, is an aglycosylated anti-TWEAK receptor antibody. BAY-356 triggers TWEAKR hyperactivation, activates NFκB and STAT1 pathways, and undergoes TWEAKR-dependent internalization. BAY-356 can be used for the research of colorectal cancer, bladder cancer, non-small cell lung cancer and pancreatic cancer[1][2].
Cat. No.: HY-P82931
Synonyms: CD266 antigen; FGF inducible 14; Fibroblast growth factor inducible immediate early response protein 14; FN14; TNFRSF 12A; tweak receptor; tweakR

Host:  

Rabbit

Application:  

WB, IHC-P, IP

Reactivity:  

Human, Mouse, Rat

Cat. No.: HY-P82931A
Synonyms: CD266 antigen; FGF inducible 14; Fibroblast growth factor inducible immediate early response protein 14; FN14; TNFRSF 12A; tweak receptor; tweakR

Host:  

Rabbit

Application:  

WB, IHC-P, IP

Reactivity:  

Human, Mouse, Rat

Cat. No.: HY-P810450
Synonyms: FN14, TNFRSF 12A, tweak receptor, tweakR,

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IF-Tissue, IP

Reactivity:  

Human, Mouse, Rat

Cat. No.: HY-P72435
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF12A; Fibroblast growth factor-inducible immediate-early response protein 14; FN14; CD266 antigen and tweak-receptor
Species:  
Source:  
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