(R)-Octopamine

Cat. No.: HY-N11141 Purity: 95.22% ee.: 100.00%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

(R)-Octopamine is a Gs-coupled receptor agonist. (R)-Octopamine binds to the orthosteric site of BmOAR2 and interacts with the Asp115, Ser202 and Tyr300 residues to activate the receptor, which couples to Gs protein and thereby stimulates adenylate cyclase activity.

For research use only. We do not sell to patients.

(R)-Octopamine Chemical Structure

CAS No. : 876-04-0

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	Get quote 7 - 9 weeks 6 - 8 weeks 8 - 10 weeks 7 - 9 weeks	Estimated Time of Arrival: December 31
25 mg	Get quote 7 - 9 weeks 6 - 8 weeks 8 - 10 weeks 7 - 9 weeks	Estimated Time of Arrival: December 31
50 mg	Get quote 7 - 9 weeks 6 - 8 weeks 8 - 10 weeks 7 - 9 weeks	Estimated Time of Arrival: December 31
100 mg	Get quote 7 - 9 weeks 6 - 8 weeks 8 - 10 weeks 7 - 9 weeks	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

In Vitro

(R)-Octopamine (0.1 nM-10 μM; 20 min after IBMX preincubation) potently activates wild-type BmOAR2 in HEK-293 cells to elevate intracellular cAMP levels, with an EC₅₀ of approximately 1.0 nM and maximum response at 10 nM^[1].
(R)-Octopamine interacts with BmOAR2 via hydrogen bonds between its phenolic OH group and Ser202/Tyr300, and between its NH₂/β-OH groups and Asp115^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

153.18

Formula

C₈H₁₁NO₂

CAS No.

876-04-0

Appearance

Solid

Color

White to light yellow

SMILES

NC[C@@H](C1=CC=C(C=C1)O)O

Structure Classification

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Purity: 95.22% ee.: 100.00%

Select Batch:

Data Sheet (265 KB) SDS (393 KB)

COA (245 KB) HNMR (249 KB) RP-HPLC (268 KB) NP-HPLC (134 KB) LCMS (140 KB)

Handling Instructions (2659 KB)

References

[1]. Xi Chen, et al. Amino acid residues involved in the interaction with the intrinsic agonist (R)-octopamine in the .BETA.-adrenergic-like octopamine receptor from the silkworm Bombyx mori. Journal of Pesticide Science 36(4):473-480.

(R)-Octopamine Related Classifications

Others

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(R)-Octopamine876-04-0Asp115intracellular cAMPGs proteinS206A mutant BmOAR2HEK-293 cellsadenylate cyclaseBombyx moriSer202Tyr300β-adrenergic-like octopamine receptor (BmOAR2)Inhibitorinhibitorinhibit

Your Recently Viewed Products:

Product Name

Requested Quantity *

Applicant Name *

Salutation

Email Address *

Phone Number *

Department

Organization Name *

City

State

Country or Region *

Remarks

Product Name

Lot #

Applicant Name *

Email Address *

Phone Number

Department *