(R)-Octopamine
Based on 1 Customer Validation
(R)-Octopamine is a Gs-coupled receptor agonist. (R)-Octopamine binds to the orthosteric site of BmOAR2 and interacts with the Asp115, Ser202 and Tyr300 residues to activate the receptor, which couples to Gs protein and thereby stimulates adenylate cyclase activity.
For research use only. We do not sell to patients.
- Purity: 95.22%
- CAS No.: 876-04-0
- Formula: C8H11NO2
- Molecular Weight:153.18
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Adrenergic Receptor Isoforms
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Biological Activity
(R)-Octopamine (0.1 nM-10 μM; 20 min after IBMX preincubation) potently activates wild-type BmOAR2 in HEK-293 cells to elevate intracellular cAMP levels, with an EC50 of approximately 1.0 nM and maximum response at 10 nM[1].
(R)-Octopamine interacts with BmOAR2 via hydrogen bonds between its phenolic OH group and Ser202/Tyr300, and between its NH2/β-OH groups and Asp115[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 876-04-0
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Appearance Solid
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Molecular Weight 153.18
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Formula C8H11NO2
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Color White to light yellow
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SMILES
NC[C@@H](C1=CC=C(C=C1)O)O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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