ASPH Protein, Mouse (His)
ASPH proteins exhibit enzymatic specificity by selectively hydroxylating aspartate (Asp) or asparagine (Asn) residues within specific epidermal growth factor-like (EGF) domains of the protein. This site-specific hydroxylation regulates post-translational modifications of EGF-containing proteins, potentially affecting their conformation, stability, or interactions. ASPH Protein, Mouse (His) is the recombinant mouse-derived ASPH protein, expressed by E. coli , with N-His labeled tag.
- Species: Mouse
- Source: E. coli
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Biological Activity
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Product Properties
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Biological Activity
ASPH proteins exhibit enzymatic specificity by selectively hydroxylating aspartate (Asp) or asparagine (Asn) residues within specific epidermal growth factor-like (EGF) domains of the protein. This site-specific hydroxylation regulates post-translational modifications of EGF-containing proteins, potentially affecting their conformation, stability, or interactions. ASPH Protein, Mouse (His) is the recombinant mouse-derived ASPH protein, expressed by E. coli , with N-His labeled tag.
ASPH protein demonstrates specificity in its enzymatic function, as it selectively hydroxylates an aspartic acid (Asp) or asparagine (Asn) residue within specific epidermal growth factor-like (EGF) domains of various proteins. This site-specific hydroxylation activity contributes to the post-translational modification of proteins containing EGF-like domains, potentially influencing their structural conformation, stability, or interaction capabilities. ASPH's specificity in targeting Asp or Asn residues within these domains underscores its role as a key regulator in modulating the functional properties of EGF-containing proteins, highlighting its significance in cellular signaling pathways and molecular processes influenced by EGF-like domains.
Technical Parameters
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Species Mouse
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Source E. coli
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Tag N-8*His
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Accession
Q8BSY0-1 (I324-I741)
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Molecular Construction
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N-term
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8*His
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ASPH (I324-I741)
Accession # Q8BSY0-1 -
C-term
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Protein Length
Partial
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Synonyms
ASPH; Junctin; Aspartate Beta-Hydroxylase; Humbug; BAH; Aspartate Beta-Hydroxylase Isoform F; CASQ2BP1; Alternative Protein ASPH; JCTN; Cardiac Junctin; HAAH; A Beta H-J-J; Aspartyl/Asparaginyl Beta-Hydroxylase; ASPH Protein; Peptide-Aspartate Beta-Dioxyg
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AA Sequence
IKAELDAAEKLRKRGKIEEAVNAFEELVRKYPQSPRARYGKAQCEDDLAEKQRSNEVLRRAIETYQEAADLPDAPTDLVKLSLKRRSERQQFLGHMRGSLLTLQRLVQLFPSDTTLKNDLGVGYLLLGDNDSAKKVYEEVLNVTPNDGFAKVHYGFILKAQNKISESIPYLKEGIESGDPGTDDGRFYFHLGDAMQRVGNKEAYKWYELGHKRGHFASVWQRSLYNVNGLKAQPWWTPRETGYTELVKSLERNWKLIRDEGLMVMDKAKGLFLPEDENLREKGDWSQFTLWQQGRKNENACKGAPKTCALLEKFSETTGCRRGQIKYSIMHPGTHVWPHTGPTNCRLRMHLGLVIPKEGCKIRCANETRTWEEGKVLIFDDSFEHEVWQDASSFRLIFIVDVWHPELTPQQRRSLPAI
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Predicted Molecular Mass
49.4 kDa
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Molecular Weight
Approximately 49 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 95%, as determined by Bis-Tris PAGE.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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