ASPH Protein, Mouse (His)

ASPH proteins exhibit enzymatic specificity by selectively hydroxylating aspartate (Asp) or asparagine (Asn) residues within specific epidermal growth factor-like (EGF) domains of the protein. This site-specific hydroxylation regulates post-translational modifications of EGF-containing proteins, potentially affecting their conformation, stability, or interactions. ASPH Protein, Mouse (His) is the recombinant mouse-derived ASPH protein, expressed by E. coli , with N-His labeled tag. The total length of ASPH Protein, Mouse (His) is 418 a.a., with molecular weight of ~49.4 kDa.

ASPH protein demonstrates specificity in its enzymatic function, as it selectively hydroxylates an aspartic acid (Asp) or asparagine (Asn) residue within specific epidermal growth factor-like (EGF) domains of various proteins. This site-specific hydroxylation activity contributes to the post-translational modification of proteins containing EGF-like domains, potentially influencing their structural conformation, stability, or interaction capabilities. ASPH's specificity in targeting Asp or Asn residues within these domains underscores its role as a key regulator in modulating the functional properties of EGF-containing proteins, highlighting its significance in cellular signaling pathways and molecular processes influenced by EGF-like domains.

Mouse

E. coli

N-His

Q8BSY0 (I324-I741)

65973  [NCBI]

Approximately 49.4 kDa

Greater than 95% as determined by Tris-Bis PAGE.

<1 EU/μg, determined by LAL method.