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Cat. No.: HY-N6955

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Eupalinilide B

Eupalinilide B is a guaiane type sesquiterpene lactone that can be found in Eupatorium lindleyanum. Eupalinilide B shows potent cytotoxicity against P-388 and A-549 tumor cell lines.

For research use only. We do not sell to patients.

CAS No.: 757202-08-7
Formula: C₂₀H₂₄O₆
Molecular Weight:360.40

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Eupalinilide B Chemical Structure

CAS No.: 757202-08-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Eupalinilide B is a guaiane type sesquiterpene lactone that can be found in Eupatorium lindleyanum. Eupalinilide B shows potent cytotoxicity against P-388 and A-549 tumor cell lines^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	0.75 μg/mL Compound: 2, Eupalinilide B	Cytotoxicity against human A549 cells after 24 hrs Cytotoxicity against human A549 cells after 24 hrs	[PMID: 15387644]
P388	IC₅₀	0.21 μg/mL Compound: 2, Eupalinilide B	Cytotoxicity against mouse P388 cells after 24 hrs Cytotoxicity against mouse P388 cells after 24 hrs	[PMID: 15387644]

In Vitro

Eupalinilide B (0.1-10 μM) shows potent cytotoxicity against A-549, BGC-823, SMMC-7721 and HL-60 tumour cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 757202-08-7
Molecular Weight 360.40
Formula C₂₀H₂₄O₆
SMILES

C[C@@]1([C@]([C@@]2([H])C=C1)([H])[C@](O3)([H])[C@@](C(C3=O)=C)([H])[C@H](OC(/C(C)=C/CO)=O)CC2=C)O
Structure Classification
- Terpenoids
- Sesquiterpenes
Initial Source
- Plants
- Compositae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Huo J, et, al. Cytotoxic sesquiterpene lactones from Eupatorium lindleyanum. J Nat Prod. 2004 Sep;67(9):1470-5. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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