1 Result for "

Berlambine

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Berlambine" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-N5027
CAS No.: 549-21-3
Synonyms: Oxyberberin; Berlambine; 8-Oxoberberine
Oxyberberine (Oxyberberin; Berlambine) is an orally effective heme oxygenase HO-1 agonist that can activate antioxidant mechanisms by regulating the PI3K/Akt/AMPK signaling pathway. Oxyberberine induces HO-1 expression, increases SOD and GSH-Px activity, inhibits NF-κB-mediated inflammatory responses, and improves insulin sensitivity and glucose metabolism. Oxyberberine has anti-diabetic, neuroprotective, anti-inflammatory and antioxidant effects, and can be used to study type 2 diabetes, traumatic brain injury (TBI) and inflammatory bowel disease .
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