3 Results for "

1099-87-2

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "1099-87-2" in MCE Product Catalog:

4
Dehydroepiandrosterone sulfate sodium
Dehydroepiandrosterone sulfate sodium
0 Images
4 Cited Publications
Cat. No.: HY-B0765
CAS No.: 1099-87-2
Synonyms: DHEA sulfate sodium; Prasterone sulfate sodium
Category:  

Metabolic Disease Endogenous metabolite Disease Research Fields Steroids

Target:  

GABA Receptor Sigma Receptor iGluR PPAR NF-κB

Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) sodium salt is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate sodium salt has both non-competitive antagonist activity of GABAA receptor and agonist activity of σ1 receptor. Dehydroepiandrosterone sulfate sodium salt can partially penetrate the blood-brain barrier, inhibit GABAA receptor-mediated chloride influx, enhance NMDA receptor activity through σ1 receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate sodium salt participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate sodium salt may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .
loading...
    loading...
View All Sizes
Dehydroepiandrosterone sulfate sodium (Standard)
Dehydroepiandrosterone sulfate sodium (Standard)
0 Images
Cat. No.: HY-B0765R
CAS No.: 1099-87-2
Synonyms: DHEA sulfate sodium (Standard); Prasterone sulfate sodium (Standard)
Category:  

Endogenous metabolite Steroids

Target:  

Reference Standards GABA Receptor Sigma Receptor iGluR PPAR NF-κB

Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) sodium salt (Standard) is the analytical standard of Dehydroepiandrosterone sulfate sodium salt (HY-B0765). This product is intended for research and analytical applications. Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate has both non-competitive antagonist activity of GABAA receptor and agonist activity of σ1 receptor. Dehydroepiandrosterone sulfate can partially penetrate the blood-brain barrier, inhibit GABAA receptor-mediated chloride influx, enhance NMDA receptor activity through σ1 receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .
loading...
    loading...
View All Sizes
4
Dehydroepiandrosterone sulfate
Dehydroepiandrosterone sulfate
0 Images
4 Cited Publications
Cat. No.: HY-113416
CAS No.: 651-48-9
Purity:  99.93%
Synonyms: DHEA sulfate; Prasterone sulfate
Category:  

Human Gut Microbiota Metabolites Microorganisms Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite

Target:  

GABA Receptor Sigma Receptor iGluR PPAR NF-κB

Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate has both non-competitive antagonist activity of GABAA receptor and agonist activity of σ1 receptor. Dehydroepiandrosterone sulfate can partially penetrate the blood-brain barrier, inhibit GABAA receptor-mediated chloride influx, enhance NMDA receptor activity through σ1 receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .
loading...
    loading...
View All Sizes
Assay Types