12 Results for "

2-dioxygenase

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "2-dioxygenase" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-113283
CAS No.: 451-13-8
Purity:  99.46%
Homogentisic acid is an orally active, blood-brain barrier-permeable amyloidogenic compound that functions as both an amyloid component and a pigment precursor. Accumulation of homogentisic acid downregulates tight junction proteins (such as claudin-5, occludin, ZO-1) and impairs blood-brain barrier integrity. Homogentisic acid and its oxidation product benzoquinone acetic acid not only induce the aggregation and fibrosis of multiple proteins (such as 1-42, α-synuclein, SAA, Transthyretin (TTR), atrial natriuretic peptide), but also trigger oxidative stress, damage to the Wnt/β-catenin pathway, and neurotoxicity, leading to ochronosis pigment deposition and synaptic dysfunction. At specific concentrations, homogentisic acid exerts no cytotoxicity or genotoxicity on human peripheral blood lymphocytes, and even counteracts the genotoxicity induced by Irinotecan (HY-16562). Homogentisic acid serves as an important tool molecule for investigating the mechanisms of diseases including ochronosis, secondary amyloidosis, Alzheimer's disease, and colorectal cancer [2] .
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Cat. No.: HY-133597
CAS No.: 2138-22-9
Purity:  99.26%
Target:  

Drug Derivative

Research Areas:  

Others

4-Chlorocatechol is a major degradation product of 4-chloro-2-aminophenol (4C2AP). 4-Chlorocatechol is also a substrate for catechol 1,2-dioxygenases and chlorocatechol dioxygenase [2].
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Cat. No.: HY-133609
CAS No.: 13673-92-2
Purity:  98.07%
Category:  

Microorganisms

3,5-Dichlorocatechol is a substrate of the broad-spectrum chlorocatechol 1,2-dioxygenase of pseudomonas chlororaphis RW71 .
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Cat. No.: HY-E71519
Research Areas:  

Others

2-Deoxymugineic-acid 2'-dioxygenase (EC 1.14.11.24) requires ferrous iron. 2-Deoxymugineic-acid 2'-dioxygenase (EC 1.14.11.24) catalyzes the hydroxylation of 3-epimylated-2'-deoxymugineic acid to 3-epimylated mugine.
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Cat. No.: HY-P87235
Synonyms: 2-dioxygenase antibody

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human

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Cat. No.: HY-133612
CAS No.: 3938-16-7
Research Areas:  

Infection

3,6-Dichlorocatechol is a substrate of the broad-spectrum chlorocatechol 1,2-dioxygenase of pseudomonas chlororaphis RW71 .
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Cat. No.: HY-W016584
CAS No.: 3428-24-8
Target:  

Others

Research Areas:  

Infection

4,5-Dichlorocatechol is a substrate of the broad-spectrum chlorocatechol 1,2-dioxygenase of pseudomonas chlororaphis RW71. The Ki values for 4,5-dichlorocatechol is 30 nM for the dioxygenase of the Chlorobenzoate-degrading strain Pseudomonas putida AC27 and 4 nM for the dioxygenase of Acidovorax sp. strain PS14 .
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Cat. No.: HY-E71536
Research Areas:  

Others

2-Halobenzoate 1,2-dioxygenase (EC 1.14.12.13) is a multicomponent enzyme system composed of a dioxygenase component and an electron transfer component.
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Cat. No.: HY-E71388
Research Areas:  

Others

1-Hydroxy-2-naphthoate 1,2-dioxygenase (EC 1.13.11.38) requires Fe2+.
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Cat. No.: HY-E71066
Research Areas:  

Others

(3R,6E)-Nerolidol synthase (EC 1.13.11.80) , characterized from bacteria Streptomyces toyocaensis and Amycolatopsis orientalis, is involved in the biosynthesis of (3,5-dihydroxyphenyl) glycine, a component of the glycopeptide antibiotic vancomycin.
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Cat. No.: HY-133597R
CAS No.: 2138-22-9
Research Areas:  

Others

4-Chlorocatechol (Standard) is the analytical standard of 4-Chlorocatechol. This product is intended for research and analytical applications. 4-Chlorocatechol is a major degradation product of 4-chloro-2-aminophenol (4C2AP). 4-Chlorocatechol is also a substrate for catechol 1,2-dioxygenases and chlorocatechol dioxygenase [2].
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Cat. No.: HY-E71444
Research Areas:  

Others

2,6-Dioxo-6-phenylhexa-3-enoate hydrolase (EC 3.7.1.8) cleaves the products from biphenol, 3-isopropylcatechol and 3-methylcatechol produced by EC 1.13.11.39 biphenyl-2,3-diol 1,2-dioxygenase, by ring-fission at a -CO-C bond.
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