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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
20S protease
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "20S protease" in MCE Product Catalog:
Target:
Research Areas:
20S Proteasome activator 1 is a potent 20S proteasome activator with EC200 values of 0.3 μM, 0.7 μM and 1.8 μM for trypsin-like site, chymotrypsin-like site and caspase-like site. 20S Proteasome activator 1 translates well in a cellular system, preventing the accumulation of the pathogenic A53T mutant of α-synuclein. 20S Proteasome activator 1 can be used for researching neurodegenerative diseases .
Cat. No.: HY-129867
CAS No.: 152015-61-7
Synonyms: Z-LLL-AMC
Target:
Research Areas:
Cat. No.: HY-118522
CAS No.: 688737-95-3
TP-110 is a proteasome inhibitor. TP-110 specifically inhibits the protease-like activity of the 20S proteasome, but does not affect the trypsin-like or peptidyl-glutamyl peptide hydrolysis activity. TP-110 inhibits the NF-κB pathway, activates caspase-8, -9, and -3, and causes PARP cleavage, significantly reducing the levels of cIAP-1 and XIAP. TP-110 causes cell cycle arrest at the G2/M phase and promotes apoptosis of cancer cells. TP-110 can be used in cancer research of prostate cancer and multiple myeloma, etc .
Cat. No.: HY-P75989
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PSMB6; Macropain Delta Chain; Proteasome 20S Subunit Beta 6; Proteasome Subunit Y; DELTA; Beta-1; Y; LMPY; Proteasome (Prosome, Macropain) Subunit, Beta Type, 6; PSY Large Multifunctional protease Y; Multicatalytic Endopeptidase Complex Delta Chain; Prote
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
