2761578-18-9
Chemical Structure
20S Proteasome activator 1
- CAS No.: 2761578-18-9
- Formula:C27H19ClF2N2OS
- Molecular Weight:492.97
IUPAC Name: 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-bis(4-fluorophenyl)propanamide
InChIKey: ZFFNQHQEQWDWBM-UHFFFAOYSA-N
SMILES: O=C(N(C1=CC=C(F)C=C1)C2=CC=C(F)C=C2)CCN3C4=C(C=CC=C4)SC5=CC=C(Cl)C=C35
Biological Activity: 20S Proteasome activator 1 is a potent 20S proteasome activator with EC200 values of 0.3 μM, 0.7 μM and 1.8 μM for trypsin-like site, chymotrypsin-like site and caspase-like site. 20S Proteasome activator 1 translates well in a cellular system, preventing the accumulation of the pathogenic A53T mutant of α-synuclein. 20S Proteasome activator 1 can be used for researching neurodegenerative diseases[1].
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20S Proteasome activator 1 | 99.87% | 20S Proteasome activator 1 is a potent 20S proteasome activator with EC200 values of 0.3 μM, 0.7 μM and 1.8 μM for trypsin-like site, chymotrypsin-like site and caspase-like site. 20S Proteasome activator 1 translates well in a cellular system, preventing the accumulation of the pathogenic A53T mutant of α-synuclein. 20S Proteasome activator 1 can be used for researching neurodegenerative diseases. | ||||||||||||||||||||
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Keywords
