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5'-CMPS

" in MedChemExpress (MCE) Product Catalog:

32

Inhibitors & Agonists

4

Biochemical Assay Reagents

7

Natural
Products

5

Isotope-Labeled Compounds

4

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-112942A
    CMP-Sialic acid sodium salt
    4 Publications Verification

    CMP-Neu5Ac sodium salt

    		 Endogenous Metabolite Metabolic Disease
    CMP-Sialic acid (CMP-Neu5Ac) sodium salt is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. CMP-Sialic acid sodium salt provides a substrate for Golgi sialyltransferases. CMP-Sialic acid sodium salt is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates .
    CMP-Sialic acid sodium salt
  • HY-E70024
    CMP-sialic acid synthetase (NmCSS)

    		Sialyltransferase Others
    CMP-sialic acid synthetase (NmCSS) is an essential enzyme involved in the biosynthesis of carbohydrates and glycoconjugates containing sialic acids. CMP-sialic acid synthetase (NmCSS) activates free Sia, converting it to CMP-Sia, which is the only donor substrate for all sialyltransferases .
    CMP-sialic acid synthetase (NmCSS)
  • HY-133073
    CCR7 Ligand 1
    3 Publications Verification

    CCR7-Cmp2105

    		 CCR Ligands for Target Protein for PROTAC Cancer
    CCR7 Ligand 1 (CCR7-Cmp2105) is an allosteric Ligand and antagonist for human CC chemokine receptor 7 (CCR7) with a Kd of 3 nM. CCR7 Ligand 1, thiadiazole-dioxide ligan, suppresses arrestin binding in response to activation by CCL19 with an IC50 of 7.3 μM .
    CCR7 Ligand 1
  • HY-112942
    CMP-Sialic acid

    CMP-Neu5Ac

    		 Endogenous Metabolite Metabolic Disease
    CMP-Sialic acid (CMP-Neu5Ac) is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. CMP-Sialic acid provides a substrate for Golgi sialyltransferases. CMP-Sialic acid is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates .
    CMP-Sialic acid
  • HY-W008915
    Cytidine 5'-diphosphate trisodium salt

    CDP

    		 DNA/RNA Synthesis Metabolic Disease
    Cytidine 5'-diphosphate trisodium salt (CDP) is produced by the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosphate kinase (UMPK). Cytidine 5′-diphosphate can be used to produce Cytidine triphosphate (CTP) for synthesis of DNA and RNA .
    Cytidine 5'-diphosphate trisodium salt
  • HY-148511
    Vidutolimod

    CMP-001

    		 Toll-like Receptor (TLR) IFNAR PD-1/PD-L1 Indoleamine 2,3-Dioxygenase (IDO) Cancer
    Vidutolimod (CMP-001) is a virus-like particle containing a TLR9 activator . Vidutolimod induces human peripheral blood mononuclear cells to secrete IFNα, and upregulates the gene expression of CXCL10, PDL1, IDO and CD80. Vidutolimod activates TLR9, which in turn triggers plasmacytoid dendritic cell activation, production of IFNγ and TNFα, induction of CXCL10, and recruitment of antitumor T cells. Vidutolimod causes influenza-like symptoms, hypotension and tumor regression, and its activity depends on the presence of anti-Qβ antibodies. Vidutolimod modulates monocyte function, promotes CD4 T cell proliferation, and activates multiple immune cell types in an environment with anti-Qβ antibodies. Vidutolimod prolongs the survival of tumor-bearing mice. Vidutolimod is used in research related to advanced melanoma, head and neck squamous cell carcinoma, and advanced non-small cell lung cancer .
    Vidutolimod
  • HY-W009162S5
    Cytidine 5′-monophosphate-13C9,15N3 dilithium

    5'-Cytidylic acid-13C9,15N3 dilithium; 5'-CMP-13C9,15N3 dilithium

    		 Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    Cytidine 5′-monophosphate- 13C9, 15N3 (5'-Cytidylic acid- 13C9, 15N3 dilithium; 5'-CMP- 13C9, 15N3) dilithium is 13C and 15N-labeled Cytidine 5'-monophosphate (HY-W009162). Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.
    Cytidine 5′-monophosphate-13C9,15N3 dilithium
  • HY-176366
    AHPC-PEG6-CH2COOH

    		E3 Ligase Ligand-Linker Conjugates Cancer
    AHPC-PEG6-CH2COOH is an E3 ligase ligand-linker conjugate that incorporates a VHL ligand and 6-unit PEG linker (HY-122702). AHPC-PEG6-CH2COOH can be used for synthesis of PROTAC CMP98 (HY-136257) .
    AHPC-PEG6-CH2COOH
  • HY-W008915R
    Cytidine 5'-diphosphate trisodium salt (Standard)

    CDP (Standard)

    		 Reference Standards DNA/RNA Synthesis Metabolic Disease
    Cytidine 5'-diphosphate (trisodium salt) (Standard) is the analytical standard of Cytidine 5'-diphosphate (trisodium salt). This product is intended for research and analytical applications. Cytidine 5'-diphosphate trisodium salt (CDP) is produced by the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosphate kinase (UMPK). Cytidine 5′-diphosphate can be used to produce Cytidine triphosphate (CTP) for synthesis of DNA and RNA[1][2].
    Cytidine 5'-diphosphate trisodium salt (Standard)
  • HY-120137
    CMP-5

    		Histone Methyltransferase Cancer
    CMP-5 is a potent, specific, and selective PRMT5 inhibitor, while displays no activity against PRMT1, PRMT4, and PRMT7 enzymes. CMP-5 selectively blocks S2Me-H4R3 by inhibiting PRMT5 methyltransferase activity on histone preparations. CMP-5 prevents Epstein-Barr virus (EBV)-driven B-lymphocyte transformation but leaving normal B cells unaffected .
    CMP-5
  • HY-W009216R
    2'-Deoxycytidine-5'-monophosphate (Standard)

    5'-dCMP (Standard); Deoxy-CMP (Standard); 2'-Deoxycytidine-5'-monophosphoric acid (Standard)

    		 Reference Standards Endogenous Metabolite Metabolic Disease
    2'-Deoxycytidine-5'-monophosphoric acid (Standard) is the analytical standard of 2'-Deoxycytidine-5'-monophosphoric acid. This product is intended for research and analytical applications. 2'-Deoxycytidine-5'-monophosphate (2'-Deoxycytidine-5'-monophosphoric acid) is an endogenous metabolite. 2'-Deoxycytidine-5'-monophosphate is a deoxynucleotide building block of which DNA is made. 2'-Deoxycytidine-5'-monophosphate can be used as a substrate of UMP/CMP kinase to form dCDP upon phosphorylation to dCTP and supports DNA biosynthesis .
    2'-Deoxycytidine-5'-monophosphate (Standard)
  • HY-112944A
    CMP-SiaNAz sodium

    CMP-NeuNAz sodium

    		 Sialyltransferase Infection
    CMP-SiaNAz (CMP-NeuNAz) sodium is a sialic acid nucleotide sugar derivative. CMP-SiaNAz sodium is integrated into the glycosidic chain through the action of STs in the Golgi apparatus, forming SiaNAz substances. CMP-SiaNAz sodium can serve as a substrate for bacterial-derived sialic acid transferases and is used for chemical enzymatic labeling and imaging of cell surface glycosides .
    CMP-SiaNAz sodium
  • HY-136257
    CMP98

    		PROTACs Others
    CMP98, a PROTAC, is unable to induce degradation of VHL. CMP98 can be used as a negative control compound for CM11 . CMP98 consists of two von Hippel-Lindau ligands on their active domain.
    CMP98
  • HY-110392
    CMP8

    		Estrogen Receptor/ERR Cancer
    CMP8, a selective ligand for estrogen receptor, binds to the mutant estrogen receptor ligand binding domain (ERLBD). CMP8 exhibits IC50 values of 29 nM , 41 nM, 1100 nM and 2200 nM for MGERα, MGRERα, hERα and hERβ, respectively .
    CMP8
  • HY-131811
    5'-CMPS

    5'-O-Thiophosphonocytidine

    		 DNA/RNA Synthesis Others
    5’CMPS (5’-O-Thiophosphonocytidine) is a 5’-CMP analog that is a potential competitive inhibitor or regulator of enzymes that interact with cytidine 5’phosphate .
    5'-CMPS
  • HY-113846A
    CMP-5 dihydrochloride

    		Histone Methyltransferase Cancer
    CMP-5 dihydrochloride is a potent, specific, and selective PRMT5 inhibitor, while displays no activity against PRMT1, PRMT4, and PRMT7 enzymes. CMP-5 dihydrochloride selectively blocks S2Me-H4R3 by inhibiting PRMT5 methyltransferase activity on histone preparations. CMP-5 dihydrochloride prevents EBV-driven B-lymphocyte transformation but leaving normal B cells unaffected .
    CMP-5 dihydrochloride
  • HY-113846
    CMP-5 hydrochloride

    		Histone Methyltransferase Cancer
    CMP-5 hydrochloride is a potent, specific, and selective PRMT5 inhibitor, while displays no activity against PRMT1, PRMT4, and PRMT7 enzymes. CMP-5 hydrochloride selectively blocks S2Me-H4R3 by inhibiting PRMT5 methyltransferase activity on histone preparations. CMP-5 hydrochloride prevents EBV-driven B-lymphocyte transformation but leaving normal B cells unaffected .
    CMP-5 hydrochloride
  • HY-170302
    CMP233

    		TRP Channel Neurological Disease
    CMP233 is a potent antagonist of TRPM4, with the IC50 of 0.15 μM. CMP233 plays an important role in neurodegenerative disorders research .
    CMP233
  • HY-171519
    2′-O-MOE-CMP

    		Nucleoside Antimetabolite/Analog Others
    2′-O-MOE-CMP is a nucleotide analog that can be used in the synthesis of oligonucleotides.
    2′-O-MOE-CMP
  • HY-171514
    2'-F-CMP

    		Nucleoside Antimetabolite/Analog Others
    2'-F-CMP is a nucleotide analog that can be used in the synthesis of oligonucleotides .
    2'-F-CMP
  • HY-153545
    9-Amino-NeuAc

    		Liposome Cancer
    9-Amino-NeuAc is a substrate of synthase. 9-Amino-NeuAc can be converted to CMP9-amino-NeuAc, activated to the corresponding CMPglycoside and transferred to asialoglycoprotein. 9-Amino-NeuAc can be used to target liposome synthesis while modulating tumor surface immunogenicity .
    9-Amino-NeuAc
  • HY-E70108
    Cytidylate kinase

    		PKC Others
    Cytidylate kinase catalyzes the phosphoryl transfer from ATP to CMP and dCMP, resulting in the formation nucleoside diphosphates .
    Cytidylate kinase
  • HY-W009162S4
    Cytidine 5′-monophosphate-15N3 dilithium

    5'-Cytidylic acid-15N3 dilithium; 5'-CMP-15N3 dilithium

    		 Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    Cytidine 5′-monophosphate- 15N3 (5'-Cytidylic acid- 15N3 dilithium; 5'-CMP- 15N3) dilithium is 15N labeled Cytidine 5'-monophosphate (HY-W009162). Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.
    Cytidine 5′-monophosphate-15N3 dilithium
  • HY-W009162S1
    Cytidine 5′-monophosphate-13C9 dilithium

    5'-Cytidylic acid-13C9 dilithium; 5'-CMP-13C9 dilithium

    		 Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    Cytidine 5′-monophosphate- 13C9 (5'-Cytidylic acid- 13C9 dilithium; 5'-CMP- 13C9) dilithium is 13C-labeled Cytidine 5'-monophosphate (HY-W009162). Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.
    Cytidine 5′-monophosphate-13C9 dilithium
  • HY-W009162S3
    Cytidine 5′-monophosphate-15N3,d12 dilithium

    5'-Cytidylic acid-15N3,d12 dilithium; 5'-CMP-15N3,d12 dilithium

    		 Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    Cytidine 5′-monophosphate- 15N3,d12 (5'-Cytidylic acid- 15N3,d12 dilithium; 5'-CMP- 15N3,d12) dilithium is deuterium and 15N labeled Cytidine 5'-monophosphate (HY-W009162). Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.
    Cytidine 5′-monophosphate-15N3,d12 dilithium
  • HY-162698
    JMF4073

    		Thymidylate Synthase Cancer
    JMF4073 is a thymidylate (TMP) and cytidylate (CMP) kinases inhibitor with IC50s of 0.16 μM and 0.17 μM, respectively. JMF4073 eliminates wild-type (WT)-Bcr-Abl-transformed myeloid cells in vitro and in vivo .
    JMF4073
  • HY-E70019
    alpha-2-3,6-sialidase (BiNanH2)

    		Endogenous Metabolite Metabolic Disease
    alpha-2-3,6-sialidase (BiNanH2) is a sialyltransferase, is often used in biochemical studies. alpha-2-3,6-sialidase (BiNanH2) catalyzes α-2,3/2,6-sialyltransfer from CMP-Neu5Ac to galactoside acceptors .
    alpha-2-3,6-sialidase (BiNanH2)
  • HY-E70152
    ST6 Sialyltransferase 4

    EC:2.4.3.7; ST6GALNAC4; SIAT3-C

    		 Biochemical Assay Reagents Cancer
    ST6 Sialyltransferase 4 (EC:2.4.3.7; ST6GALNAC4; SIAT3-C; SIAT3C; SIAT7-D; SIAT7D) catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. ST6 Sialyltransferase 4 promotes hepatocellular carcinogenesis by inducing abnormal glycosylation. .
    ST6 Sialyltransferase 4
  • HY-W009162S2
    Cytidine 5′-monophosphate-d12 dilithium

    5'-Cytidylic acid-d12 dilithium; 5'-CMP-d12 dilithium

    		 Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    Cytidine 5′-monophosphate-d12 (5'-Cytidylic acid-d12 dilithium; 5'-CMP-d12) dilithium is deuterium labeled Cytidine 5'-monophosphate (HY-W009162). Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.
    Cytidine 5′-monophosphate-d12 dilithium
  • HY-180730
    Phosphonoformyl-CMP

    CMP-5'-Phosphonoformic acid

    		 Nucleoside Antimetabolite/Analog Metabolic Disease
    Phosphonoformyl-CMP (CMP-5'-Phosphonoformic acid) is a nucleoside metabolite.
    Phosphonoformyl-CMP
  • HY-180634
    CMP-2-Aminoethylphosphonate

    		Nucleoside Antimetabolite/Analog Metabolic Disease
    CMP-2-Aminoethylphosphonate is a nucleoside metabolite.
    CMP-2-Aminoethylphosphonate
  • HY-112942B
    CMP-Sialic acid disodium

    CMP-Neu5Ac disodium

    		 Endogenous Metabolite Metabolic Disease
    CMP-Sialic acid (CMP-Neu5Ac) sodium is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. CMP-Sialic acid sodium provides a substrate for Golgi sialyltransferases. CMP-Sialic acid sodium is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates .
    CMP-Sialic acid disodium

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