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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
5-HT2CR
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "5-HT2CR" in MCE Product Catalog:
Cat. No.: HY-179008
CAS No.: 2841457-05-2
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5-HT2CR agonist 2 (Compound 16k) is a selective, blood-brain barrier-penetrating and Gq-biased 5-HT2CR agonist, with an EC50 of 36 nM. 5-HT2CR agonist 2 attenuates MK801 (HY-15084B)-induced hyperlocomotion and reverses Phencyclidine-induced hyperlocomotor activity .
Cat. No.: HY-157425
CAS No.: 1216074-15-5
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5-HT2CR agonist 1 (compound 8), a 7-chloro analogue, is a selective 5-HT2CR partial agonist (Emax=71.09%) with an EC50 value of 121.5 nM and no observed activity toward 5-HT2AR or 5-HT2BR. 5-HT2CR agonist 1 exhibits no recruitment activity for β-arrestin and shows low inhibition of hERG at 10 μM .
Cat. No.: HY-179008A
CAS No.: 2841458-00-0
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(S)-5-HT2CR agonist 1 (Compound (S)-16k) is selective 5-HT2CR agonist, with an EC50 of 14 nM. FXa-IN-2 can be used in the research of hyperlocomotion .
Cat. No.: HY-180617
CAS No.: 2376501-96-9
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5-HT2CR modulator 1 (Compound 3B) is a selective, positive ago-allosteric modulator of 5HT2CR with an EC50 of 8 nM. 5-HT2CR modulator 1 is also a selective 5HT2CR agonist with an EC50 of 25 nM. 5-HT2CR modulator 1 reduces food intake .
Cat. No.: HY-173451
CAS No.: 3024777-79-2
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TAAR1/5-H-2CR agonist-1 (compound 21b) is a TAAR1 and 5-HT2CR dual agonist with EC50s of 0.022 and 0.246 μM, respectively. TAAR1/5-H-2CR agonist-1 can used in the study of schizophrenia and Alzheimer's Disease .
Cat. No.: HY-RS20957
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Htr2c Mouse Pre-designed siRNA Set A contains three designed siRNAs for Htr2c gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-187537
Research Areas:
5-HT2AR ligand-2 is a serotonin 2A receptor (5-HT2AR) ligand with a Ki value of 11.4 nM. 5-HT2AR ligand-2 stabilizes the inactive conformation of receptors by interacting with specific amino acid residues in the orthosteric binding pockets of D2R and 5-HT2AR, thereby blocking downstream signal transduction. 5-HT2AR ligand-2 can be used in studies related to schizophrenia .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
