5-HT2CR agonist 1
5-HT2CR agonist 1 (compound 8), a 7-chloro analogue, is a selective 5-HT2CR partial agonist (Emax=71.09%) with an EC50 value of 121.5 nM and no observed activity toward 5-HT2AR or 5-HT2BR. 5-HT2CR agonist 1 exhibits no recruitment activity for β-arrestin and shows low inhibition of hERG at 10 μM.
For research use only. We do not sell to patients.
- CAS No.: 1216074-15-5
- Formula: C13H14ClNO
- Molecular Weight:235.71
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All 5-HT Receptor Isoforms
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Biological Activity
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5-HT2C Receptor 121.5 nM (EC50) |
Chemical Information
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CAS No. 1216074-15-5
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Molecular Weight 235.71
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Formula C13H14ClNO
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SMILES
ClC1=CC=C2C=CC3(OC2=C1)CCNCC3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)