2 Results for "

99-48-9

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "99-48-9" in MCE Product Catalog:

1
Carveol
Carveol
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Cat. No.: HY-W017370
CAS No.: 99-48-9
Category:  

Natural Products other families Metabolic Disease Plants Endogenous metabolite Disease Research Fields

Target:  

Bcl-2 Family Caspase TNF Receptor Interleukin Related Keap1-Nrf2 Heme Oxygenase (HO) NF-κB Apoptosis α-synuclein Amylases

Carveol is an orally active monoterpenoid alcohol with neuroprotective, antioxidant, anti-inflammatory, anticonvulsant, antidiabetic, hypolipidemic and hepatoprotective activities. Carveol upregulates the expression of Bcl2, downregulates the expression of caspase-3, TNF-α, IL1β and IL6, activates the Nrf2/HO-1 antioxidant signaling pathway, inhibits the RAGE/NF-κB signaling pathway, and suppresses neuroinflammation and neuronal apoptosis. Carveol inhibits α-synuclein aggregation, improves cognitive ability, and inhibits α-amylase activity. Carveol exerts neuroprotective effects in a rat model of Parkinson's disease. Carveol exhibits antidiabetic effects in alloxan-induced diabetic rats. Carveol alleviates PTZ-induced seizures in rats. Carveol can be used in research related to Parkinson's disease, epilepsy, diabetes and ischemic stroke .
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Carveol (Standard)
Carveol (Standard)
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Cat. No.: HY-W017370R
CAS No.: 99-48-9
Category:  

Natural Products other families Plants Endogenous metabolite

Target:  

Reference Standards Bcl-2 Family Caspase TNF Receptor Interleukin Related Keap1-Nrf2 Heme Oxygenase (HO) NF-κB Apoptosis α-synuclein Amylases

Carveol (Standard) is the analytical standard of Carveol. This product is intended for research and analytical applications. Carveol is an orally active monoterpenoid alcohol with neuroprotective, antioxidant, anti-inflammatory, anticonvulsant, antidiabetic, hypolipidemic and hepatoprotective activities. Carveol upregulates the expression of Bcl2, downregulates the expression of caspase-3, TNF-α, IL1β and IL6, activates the Nrf2/HO-1 antioxidant signaling pathway, inhibits the RAGE/NF-κB signaling pathway, and suppresses neuroinflammation and neuronal apoptosis. Carveol inhibits α-synuclein aggregation, improves cognitive ability, and inhibits α-amylase activity. Carveol exerts neuroprotective effects in a rat model of Parkinson's disease. Carveol exhibits antidiabetic effects in alloxan-induced diabetic rats. Carveol alleviates PTZ-induced seizures in rats. Carveol can be used in research related to Parkinson's disease, epilepsy, diabetes and ischemic stroke .
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