99-48-9
99-48-9
Chemical Structure
Carveol
- CAS No.: 99-48-9
- Formula:C10H16O
- Molecular Weight:152.24
IUPAC Name: 2-methyl-5-(prop-1-en-2-yl)cyclohex-2-en-1-ol
InChIKey: BAVONGHXFVOKBV-UHFFFAOYSA-N
SMILES: OC1C(C)=CCC(C(C)=C)C1
Biological Activity: Carveol is an orally active monoterpenoid alcohol with neuroprotective, antioxidant, anti-inflammatory, anticonvulsant, antidiabetic, hypolipidemic and hepatoprotective activities. Carveol upregulates the expression of Bcl2, downregulates the expression of caspase-3, TNF-α, IL1β and IL6, activates the Nrf2/HO-1 antioxidant signaling pathway, inhibits the RAGE/NF-κB signaling pathway, and suppresses neuroinflammation and neuronal apoptosis. Carveol inhibits α-synuclein aggregation, improves cognitive ability, and inhibits α-amylase activity. Carveol exerts neuroprotective effects in a rat model of Parkinson's disease. Carveol exhibits antidiabetic effects in alloxan-induced diabetic rats. Carveol alleviates PTZ-induced seizures in rats. Carveol can be used in research related to Parkinson's disease, epilepsy, diabetes and ischemic stroke[1][2][3][4].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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Carveol | 98.32% | Carveol is an orally active monoterpenoid alcohol with neuroprotective, antioxidant, anti-inflammatory, anticonvulsant, antidiabetic, hypolipidemic and hepatoprotective activities. Carveol upregulates the expression of Bcl2, downregulates the expression of caspase-3, TNF-α, IL1β and IL6, activates the Nrf2/HO-1 antioxidant signaling pathway, inhibits the RAGE/NF-κB signaling pathway, and suppresses neuroinflammation and neuronal apoptosis. Carveol inhibits α-synuclein aggregation, improves cognitive ability, and inhibits α-amylase activity. Carveol exerts neuroprotective effects in a rat model of Parkinson's disease. Carveol exhibits antidiabetic effects in alloxan-induced diabetic rats. Carveol alleviates PTZ-induced seizures in rats. Carveol can be used in research related to Parkinson's disease, epilepsy, diabetes and ischemic stroke. | ||||||||||||||||||||
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Carveol (Standard) | ≥98% | Carveol (Standard) is the analytical standard of Carveol. This product is intended for research and analytical applications. Carveol is an orally active monoterpenoid alcohol with neuroprotective, antioxidant, anti-inflammatory, anticonvulsant, antidiabetic, hypolipidemic and hepatoprotective activities. Carveol upregulates the expression of Bcl2, downregulates the expression of caspase-3, TNF-α, IL1β and IL6, activates the Nrf2/HO-1 antioxidant signaling pathway, inhibits the RAGE/NF-κB signaling pathway, and suppresses neuroinflammation and neuronal apoptosis. Carveol inhibits α-synuclein aggregation, improves cognitive ability, and inhibits α-amylase activity. Carveol exerts neuroprotective effects in a rat model of Parkinson's disease. Carveol exhibits antidiabetic effects in alloxan-induced diabetic rats. Carveol alleviates PTZ-induced seizures in rats. Carveol can be used in research related to Parkinson's disease, epilepsy, diabetes and ischemic stroke. | ||||||||||||||||||||
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trans-Sobrerol | 99.75% | trans-Sobrerol (NRM-331) is a potent mucofluidifying agent. trans-Sobrerol demonstrates an anti-amnesic effect by enhancing hippocampal cholinergic signaling, alongside exhibiting anti-tau and anti-Aβ synthesis properties. trans-Sobrerol mitigates memory impairment induced by Scopolamine (HY-N0296). trans-Sobrerol can be used in the research of Alzheimer's disease. | ||||||||||||||||||||
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Sobrerol | Sobrerol ((Rac)-NRM-331) is a monoterpene compound. Sobrerol promotes mucus clearance and improves respiratory infections. Sobrerol can be used in research on respiratory diseases. | |||||||||||||||||||||
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(S)-(-)-Perillyl alcohol (Standard) | ≥98% | (S)-(-)-Perillyl alcohol (Standard) is the analytical standard of (S)-(-)-Perillyl alcohol (HY-116514). This product is intended for research and analytical applications. (S)-(-)-Perillyl alcohol, a monoterpene, is an orally active farnesyl transferase and geranylgeranyl transferase inhibitor. (S)-(-)-Perillyl alcohol up-regulates the mannose-6-phosphate receptor, facilitating TGF-β1 activation and cytostasis,. (S)-(-)-Perillyl alcohol induces apoptosis in cancer cells, modulates cyclin D1 and AP-1 activity. (S)-(-)-Perillyl alcohol exhibits antitumor activity against sarcoma tumors in mice. (S)-(-)-Perillyl alcohol can be used for the research of squamous cell carcinoma of the esophagus and sarcoma 180. | ||||||||||||||||||||
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(-)-Carveol | (-)-Carveol is a natural unsaturated monocyclic monoterpene alcohol with the activity of regulating neural excitability. (-)-Carveol can activate or inhibit neural excitability by changing its chemical structure, which has potential significance for the design of targeted compounds. (-)-Carveol can also be used as a fragrance in cosmetics and a flavor additive in the food industry. | |||||||||||||||||||||
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Perillyl alcohol (Standard) | ≥98% | Perillyl alcohol (Standard) is the analytical standard of Perillyl alcohol (HY-N7000). Perillyl alcohol is an orally active monoterpene. Perillyl alcohol exhibits multiple activities such as analgesic, anti-inflammatory, anti-tumor, anti-angiogenic, and anti-nociceptive effects. Perillyl alcohol can induce apoptosis and cell cycle arrest in tumor cells. | ||||||||||||||||||||
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Dihydrocarveol | Dihydrocarveol is an anticancer agent. Dihydrocarveol shows inhibitory activity against human colon adenocarcinoma cells (HCT-116, HT-29, COLO320DM) with an IC50 value of 28.31 μM in HCT-116 cells. Dihydrocarveol is promising for research of colon cancer. | |||||||||||||||||||||
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(-)-Dihydrocarveol | (-)-Dihydrocarveol is a metabolite that can be extracted from actinomycetes. | |||||||||||||||||||||
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(+)-Neodihydrocarveol | (+)-Neodihydrocarveol is a monoterpenoid compound. (+)-Neodihydrocarveol is a major metabolite during the biotransformation of (-)-limonene (HY-Z0478) by the fungus Aspergillus cellulosae M-77. | |||||||||||||||||||||
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(-)-Limonene (Standard) | 99.36% | (-)-Limonene (Standard) is the analytical standard of (-)-Limonene. This product is intended for research and analytical applications. (-)-Limonene ((S)-(-)-Limonene) is a monoterpene found in citrus plants like lemon, orange, and grape. (-)-Limonene can induce a mild bronchoconstrictive effect. | ||||||||||||||||||||
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References
- [1]. Ola A. Habotta, et al. Carveol, a natural monoterpene from essential oils prevents neuronal impairments associated with murine Parkinson's disease model in rats. Journal of Agriculture and Food Research Volume 22, August 2025, 101993.
- [2]. Alvi AM, et al. Carveol Attenuates Seizure Severity and Neuroinflammation in Pentylenetetrazole-Kindled Epileptic Rats by Regulating the Signaling Pathway. Oxidative medicine and cellular longevity. 2021;2021:9966663. [Content Brief]
- [3]. Ahmed MS, et al. Computational and Pharmacological Evaluation of Carveol for Antidiabetic Potential. Frontiers in pharmacology. 2020;11:919. [Content Brief]
- [4]. Malik I, et al. Potent Natural Antioxidant Carveol Attenuates MCAO-Stress Induced Oxidative, Neurodegeneration by Regulating the Nrf-2 Pathway. Frontiers in neuroscience. 2020;14:659. [Content Brief]
