1 Result for "

A2073

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "A2073" in MCE Product Catalog:

Cat. No.: HY-174321
CAS No.: 2834742-70-8
Target:  

p38 MAPK PI3K Akt NF-κB

Research Areas:  

Cancer

A2073 is a flavagline derivative that potently inhibits the proliferation of erythroleukemia cells by causing cell cycle arrest and suppressing the MAPK, NF-κB, and PI3K signaling pathways. A2073 formes stable interactions with cell cycle-related proteins (CDK1, CCNA2, PRIM1). A2073 exhibits significant anti-proliferative activity against tumor cells while maintaining a favorable toxicity profile in a zebrafish xenograft tumor model. A2073 can be used for the study of acute erythroleukemia.
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