2 Results for "

AAF-CMK

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "AAF-CMK" in MCE Product Catalog:

Cat. No.: HY-129407A
CAS No.: 102129-66-8
Research Areas:  

Cancer

AAF-CMK is a TPPII (tripeptidylpeptidase II) inhibitor, shows anti-tumor activity and induces apoptosis. AAF-CMK can be used in leukemia research .
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Cat. No.: HY-129407
CAS No.: 184901-82-4
Synonyms: Ala-ala-phe-chloromethylketone tfa; N-Ala-Ala-Phe-CMK; Tripeptidyl Peptidase inhibitor II
Target:  

Proteasome

Research Areas:  

Infection

AAF-CMK TFA (Ala-ala-phe-chloromethylketone tfa; N-Ala-Ala-Phe-CMK) is a subtilisin-type serine peptidase that removes tripeptides from the free NH2 termini of oligopeptides. AAF-CMK TFA is an irreversible inhibitor of TPPII and is typically used at concentrations of 10-100 μM. It does not significantly interfere with the chymotrypsin-like activity of the proteasome. AAF-CMK also inhibits bleomycin hydrolase and puromycin-sensitive aminopeptidase when used at a concentration of 50 μM.
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