1 Result for "

ABri 23

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "ABri 23" in MCE Product Catalog:

Amyloid Bri Protein (1-23)
Amyloid Bri Protein (1-23)
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Cat. No.: HY-P10192
CAS No.: 717122-86-6
Synonyms: ABri peptide (1-23); ABri23
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Amyloid Bri Protein (1-23) (ABri peptide (1-23); ABri23) is a physiological 23-amino-acid peptide released from the C-terminus of the type II transmembrane protein Bri2 (ITM2B, Integral Membrane Protein 2B) following cleavage by the furin protease. Amyloid Bri Protein (1-23) interacts with the extracellular Brichos domain of Bri2 during Bri2 biosynthesis. Amyloid Bri Protein (1-23) interacts with amyloid β peptide (Aβ1-40, thereby inhibiting its aggregation and fibril formation. Amyloid Bri Protein (1-23) can be used in studies related to Alzheimer's disease and familial British dementia .
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