1 Result for "

AD-2646

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "AD-2646" in MCE Product Catalog:

Cat. No.: HY-124134
CAS No.: 366487-89-0
Synonyms: LCL102
Target:  

Ceramidase Caspase PARP

Research Areas:  

Cancer

AD-2646 (LCL102), a ceramide analog, can kill leukemic T cells (EC50: 40 μM). AD-2646 triggers the cleavage of caspase-8, -9 and -3, as well as the caspase substrate PARP. AD-2646 is a ceramidase inhibitor. AD-2646 induces an accumulation of endogenous ceramide owing to perturbed ceramide metabolism .
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