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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
ALK ligand1
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "ALK ligand1" in MCE Product Catalog:
Cat. No.: HY-W754809
CAS No.: 2353496-79-2
Research Areas:
ALK ligand-1 is a ALK ligand that can be used for synthesis of PROTAC ALK degrader-4 (HY-175527) .
Cat. No.: HY-169482
CAS No.: 2764870-80-4
Research Areas:
ALK protein ligand-1 (Compound A1), a ligand for the anaplastic lymphoma kinase (ALK) protein, is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs) that exhibits inhibitory effects on ALK. ALK protein ligand-1 can be used in the synthesis of AP-1 (HY-169481) .
Cat. No.: HY-183441
CAS No.: 3125240-66-3
Research Areas:
ALK5 ligand-1 (a31's ALK5 ligand) is a ligand of Anaplastic lymphoma kinase ALK5 with higher selectivity for ALK5 than for ALK4. ALK5 ligand-1 can be used to synthesize PROTAC degraders targeting ALK5. ALK5 PROTACs induce ALK5 degradation dependent on the ubiquitin-proteasome system and exert antifibrotic activity. ALK5 ligand-1 can be used in studies of pulmonary fibrosis .
Cat. No.: HY-184541
CAS No.: 2229036-85-3
Research Areas:
ALK protein ligand-1-PEG2-N3 is an ALK ligand intermediate with a PEG2 linker, which can be used to synthesize ALK-targeting PROTAC degraders (HY-122582). ALK protein ligand-1-PEG2-N3 is applicable to research related to non-small cell lung cancer, anaplastic large cell lymphoma, and neuroblastoma .
Cat. No.: HY-183442
Research Areas:
ALK5 ligand-1-amine-C2-piperazine-C4-OH is a conjugate of a ligand targeting ALK5 and a PROTAC linker. ALK5 ligand-1-amine-C2-piperazine-C4-OH can be used to synthesize the PROTAC degrader (a31). ALK5 PROTACs induce UPS-dependent and selective degradation of ALK5 over ALK4. ALK5 ligand-1-amine-C2-piperazine-C4-OH can be applied to research on pulmonary fibrosis .
Cat. No.: HY-P71584
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ALKAL1; AUG-Beta; Prev. FAM150A; Augmentor-Alpha; UNQ9433; Protein FAM150A; AUGB; Augmentor-Beta; Family With Sequence Similarity 150 Member A; RPLK9433; Augmentor Beta; AUGA; ALK And LTK ligand 1; Family With Sequence Similarity 150, Member A
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
